3D Self-Assembled Nanocarriers for Drug Delivery Publisher Pubmed



Karballaei Mirzahosseini H¹ ; Sheikhi M² ; Najmeddin F³ ; Shirangi M² ; Mojtahedzadeh M^{3, 4} Show Affiliations
Source: Drug Metabolism Reviews Published:2023

Abstract

There are many benefits to drug delivery from drug–carrier nanostructure systems. It might be developed to carefully control drug release rates or to deliver a precise amount of a therapeutic substance to particular body areas. Self-assembling is the process by which molecules and nanoparticles spontaneously organize into organized clusters. For instance, proteins and peptides can interact with one another to create highly organized supramolecular structures with various properties, such as helical ribbons and fibrous scaffolds. Another advantage of self-assembly is that it may be effective with a variety of materials, including metals, oxides, inorganic salts, polymers, semiconductors, and even organic semiconductors. Fullerene, graphene, and carbon nanotubes (CNTs), three of the most fundamental classes of three-dimensionally self-assembling nanostructured carbon-based materials, are essential for the development of modern nanotechnologies. Self-assembled nanomaterials are used in a variety of fields, including nanotechnology, imaging, and biosensors. This review study begins with a summary of various major 3D nanomaterials, including graphene oxide, CNTs, and nanodiamond, as well as 3D self-assembled polyfunctionalized nanostructures and adaptable nanocarriers for drug delivery. © 2023 Informa UK Limited, trading as Taylor & Francis Group.