Two-Year Follow-Up of Patients With Unstable Angina/Non-St Segment Elevation Myocardial Infarction Undergoing Early Invasive Strategy: Predictors of Normal or Near-Normal Coronary Angiography and Mortality

Two-Year Follow-Up of Patients With Unstable Angina/Non-St Segment Elevation Myocardial Infarction Undergoing Early Invasive Strategy: Predictors of Normal or Near-Normal Coronary Angiography and Mortality Publisher Pubmed

Jenab Y¹ ; Kassaian E² ; Pourhosseini HR² ; Salarifar M² ; Jalali A³ ; Talasaz AH⁴

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1. Emergency Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
2. Catheterization Laboratory Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
3. Research Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Clinical Pharmacy, School of Pharmacy, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
5. Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Critical Pathways in Cardiology Published:2018

Abstract

Background: Predictors of normal or near-normal coronary angiography (NONCAG) in patients with unstable angina/non-ST-elevation myocardial infarction (UA/NSTEMI) and their importance regarding the prognosis are not understood. Accordingly, we determined these predictors as well as mortality risk factors at 2-year follow-up of UA/NSTEMI patients managed by the early invasive strategy. Methods: We prospectively studied consecutive patients with UA/NSTEMI managed with the early invasive strategy at Tehran Heart Center, in 1-year period. Echocardiography was performed before coronary angiography (CAG) for all the patients. Baseline characteristics, laboratory parameters, echocardiographic findings, invasive treatment modalities, and survival status after 2 years of follow-up were collected. We identified the predictors of NONCAG in the first phase of the study and then the risk factors of mortality in the second phase. Results: In the study period, 298 patients including 211 (71%) males, with the age of 59.31 ± 10.72 years were enrolled. The following factors were predictors of NONCAG: the female sex (P < 0.001); negative family history of CAD (P = 0.028); Thrombolysis in Myocardial Infarction (TIMI) risk score (P < 0.001); and early transmitral flow velocity/mean mitral annular velocity (E/E′ mean ) (P = 0.003). The following items were significant protective factors against mortality: percutaneous coronary intervention (PCI) (P = 0.012), age (P = 0.001), and E/E′ mean (P = 0.020). Conclusion: Patients’ baseline characteristics as well as echocardiographic data could help in predicting those with NONCAG and PCI can be considered as the treatment of strategy with the most protection against mortality. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

Style	Citing Format
MLA	Jenab Y, et al.. "Two-Year Follow-Up of Patients With Unstable Angina/Non-St Segment Elevation Myocardial Infarction Undergoing Early Invasive Strategy: Predictors of Normal or Near-Normal Coronary Angiography and Mortality." Critical Pathways in Cardiology, vol. 17, no. 1, 2018, pp. 47-52.
APA	Jenab Y, Kassaian E, Pourhosseini HR, Salarifar M, Jalali A, Talasaz AH (2018). Two-Year Follow-Up of Patients With Unstable Angina/Non-St Segment Elevation Myocardial Infarction Undergoing Early Invasive Strategy: Predictors of Normal or Near-Normal Coronary Angiography and Mortality. Critical Pathways in Cardiology, 17(1), 47-52.
Chicago	Jenab Y, Kassaian E, Pourhosseini HR, Salarifar M, Jalali A, Talasaz AH. "Two-Year Follow-Up of Patients With Unstable Angina/Non-St Segment Elevation Myocardial Infarction Undergoing Early Invasive Strategy: Predictors of Normal or Near-Normal Coronary Angiography and Mortality." Critical Pathways in Cardiology 17, no. 1 (2018): 47-52.
Harvard	Jenab Y et al. (2018) 'Two-Year Follow-Up of Patients With Unstable Angina/Non-St Segment Elevation Myocardial Infarction Undergoing Early Invasive Strategy: Predictors of Normal or Near-Normal Coronary Angiography and Mortality', Critical Pathways in Cardiology, 17(1), pp. 47-52.
Vancouver	Jenab Y, Kassaian E, Pourhosseini HR, Salarifar M, Jalali A, Talasaz AH. Two-Year Follow-Up of Patients With Unstable Angina/Non-St Segment Elevation Myocardial Infarction Undergoing Early Invasive Strategy: Predictors of Normal or Near-Normal Coronary Angiography and Mortality. Critical Pathways in Cardiology. 2018;17(1):47-52.
BibTex	@article{ author = {Jenab Y and Kassaian E and Pourhosseini HR and Salarifar M and Jalali A and Talasaz AH}, title = {Two-Year Follow-Up of Patients With Unstable Angina/Non-St Segment Elevation Myocardial Infarction Undergoing Early Invasive Strategy: Predictors of Normal or Near-Normal Coronary Angiography and Mortality}, journal = {Critical Pathways in Cardiology}, volume = {17}, number = {1}, pages = {47-52}, year = {2018} }
RIS	TY - JOUR AU - Jenab Y AU - Kassaian E AU - Pourhosseini HR AU - Salarifar M AU - Jalali A AU - Talasaz AH TI - Two-Year Follow-Up of Patients With Unstable Angina/Non-St Segment Elevation Myocardial Infarction Undergoing Early Invasive Strategy: Predictors of Normal or Near-Normal Coronary Angiography and Mortality JO - Critical Pathways in Cardiology VL - 17 IS - 1 SP - 47 EP - 52 PY - 2018 ER -

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