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From Nature to Nanotech: Harnessing the Power of Electrospun Polysaccharide-Based Nanofibers As Sustainable Packaging Publisher Pubmed



Tayebikhorrami V1 ; Shahgordi S2 ; Dabbaghi MM2 ; Fadaei MS2 ; Masoumi Shahrbabak S3 ; Fallahianshafiei S4 ; Fadaei MR1 ; Hasnain MS5 ; Nayak AK6 ; Askari VR2
Authors
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Authors Affiliations
  1. 1. Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran
  3. 3. Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Pharmacy, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
  5. 5. Department of Pharmacy, Palamau Institute of Pharmacy, Chianki, Jharkhand, Daltonganj, India
  6. 6. Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Odisha, Bhubaneswar, India

Source: International Journal of Biological Macromolecules Published:2025


Abstract

Today, the applications of natural polysaccharide-based nanofibers are growing in drug delivery and food industries. They also showed their capability as packaging due to biodegradability, mechanical strength, barrier properties, thermal stability, antioxidant, and antimicrobial features. Natural polysaccharides come from different sources, such as plants, microbes, and animals. Natural polysaccharide-based nanofibers can be considered sustainable packaging in contrast to plastic packaging due to their safety and biodegradability. Smart packaging is a new trend in packaging materials, and natural polysaccharides can be applied as smart packaging. They can work as an indicator that confirms food health in food packaging. Electrospinning is one of the most used methods for the fabrication of nanofibers, and it can also be used for the fabrication of natural polysaccharide nanofibers. This method can be scaled up and used to fabricate nanofibers on a large scale. This paper will review recent studies on natural polysaccharide-based nanofiber as packaging materials and their benefits. We also discuss the challenges and limitations of their scale-up and electrospinning process. Furthermore, we will discuss the future perspective of natural polysaccharide-based nanofiber as a new sustainable packaging. © 2025 Elsevier B.V.
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