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The Food and Biomedical Applications of Curcumin-Loaded Electrospun Nanofibers: A Comprehensive Review Publisher



Rostami M1, 2 ; Kolahi Azar H3 ; Salehi M4, 5 ; Abedin Dargoush S6 ; Rostamani H7 ; Jahedkhaniki G1 ; Alikord M1 ; Aghabeigi R8 ; Ahmadi A9 ; Beheshtizadeh N4, 5 ; Webster TJ10, 11, 12 ; Rezaei N13, 14, 15
Authors
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Authors Affiliations
  1. 1. Division of Food Safety and Hygiene, Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Food Science and Nutrition Group (FSAN), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  3. 3. Department of Pathology, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Department of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Regenerative Medicine Group (REMED), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  6. 6. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
  7. 7. Department of Biomedical Engineering-Biomaterials, Islamic Azad University, Mashhad, Iran
  8. 8. Department of Medical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran
  9. 9. Department of Food Sciences and Technology, Tabriz University of Medical Sciences, Tabriz, Iran
  10. 10. School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin, China
  11. 11. Programa de Pos-Graduacao em Ciencia e Engenharia dos Materiais, Universidade Federal do Piaui, Teresina, Brazil
  12. 12. School of Engineering, Saveetha University, Chennai, India
  13. 13. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  14. 14. Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  15. 15. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Critical Reviews in Food Science and Nutrition Published:2023


Abstract

Encapsulating curcumin (CUR) in nanocarriers such as liposomes, polymeric micelles, silica nanoparticles, protein-based nanocarriers, solid lipid nanoparticles, and nanocrystals could be efficient for a variety of industrial and biomedical applications. Nanofibers containing CUR represent a stable polymer-drug carrier with excellent surface-to-volume ratios for loading and cell interactions, tailored porosity for controlled CUR release, and diverse properties that fit the requirements for numerous applications. Despite the mentioned benefits, electrospinning is not capable of producing fibers from multiple polymers and biopolymers, and the product’s effectiveness might be affected by various machine- and material-dependent parameters like the voltage and the flow rate of the electrospinning process. This review delves into the current and innovative recent research on nanofibers containing CUR and their various applications. © 2023 Taylor & Francis Group, LLC.
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