Paper-Based Biosensors As Point-Of-Care Diagnostic Devices for the Detection of Cancers: A Review of Innovative Techniques and Clinical Applications

Paper-Based Biosensors As Point-Of-Care Diagnostic Devices for the Detection of Cancers: A Review of Innovative Techniques and Clinical Applications Publisher

Mahmoodpour M¹ ; Kiasari BA² ; Karimi M³ ; Abroshan A⁴ ; Shamshirian D⁵ ; Hosseinalizadeh H¹ ; Delavari A⁶ ; Mirzei H⁷

Show Affiliations

1. Department of Medical Biotechnology, Faculty of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran
2. Virology Department, Faculty of Veterinary, The University of Tehran, Tehran, Iran
3. Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran
4. Student Research Committee, Faculty of Veterinary Medicine, Shahid Bahonar University, Kerman, Iran
5. Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
6. Student's Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
7. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran

Source: Frontiers in Oncology Published:2023

Abstract

The development and rapid progression of cancer are major social problems. Medical diagnostic techniques and smooth clinical care of cancer are new necessities that must be supported by innovative diagnostic methods and technologies. Current molecular diagnostic tools based on the detection of blood protein markers are the most common tools for cancer diagnosis. Biosensors have already proven to be a cost-effective and accessible diagnostic tool that can be used where conventional laboratory methods are not readily available. Paper-based biosensors offer a new look at the world of analytical techniques by overcoming limitations through the creation of a simple device with significant advantages such as adaptability, biocompatibility, biodegradability, ease of use, large surface-to-volume ratio, and cost-effectiveness. In this review, we covered the characteristics of exosomes and their role in tumor growth and clinical diagnosis, followed by a discussion of various paper-based biosensors for exosome detection, such as dipsticks, lateral flow assays (LFA), and microfluidic paper-based devices (µPADs). We also discussed the various clinical studies on paper-based biosensors for exosome detection. Copyright © 2023 Mahmoodpour, Kiasari, Karimi, Abroshan, Shamshirian, Hosseinalizadeh, Delavari and Mirzei.

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Hamid Reza Mirzaei (9)

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Style	Citing Format
MLA	Mahmoodpour M, et al.. "Paper-Based Biosensors As Point-Of-Care Diagnostic Devices for the Detection of Cancers: A Review of Innovative Techniques and Clinical Applications." Frontiers in Oncology, vol. 13, no. , 2023, pp. -.
APA	Mahmoodpour M, Kiasari BA, Karimi M, Abroshan A, Shamshirian D, Hosseinalizadeh H, Delavari A, Mirzei H (2023). Paper-Based Biosensors As Point-Of-Care Diagnostic Devices for the Detection of Cancers: A Review of Innovative Techniques and Clinical Applications. Frontiers in Oncology, 13(), -.
Chicago	Mahmoodpour M, Kiasari BA, Karimi M, Abroshan A, Shamshirian D, Hosseinalizadeh H, Delavari A, Mirzei H. "Paper-Based Biosensors As Point-Of-Care Diagnostic Devices for the Detection of Cancers: A Review of Innovative Techniques and Clinical Applications." Frontiers in Oncology 13, no. (2023): -.
Harvard	Mahmoodpour M et al. (2023) 'Paper-Based Biosensors As Point-Of-Care Diagnostic Devices for the Detection of Cancers: A Review of Innovative Techniques and Clinical Applications', Frontiers in Oncology, 13(), pp. -.
Vancouver	Mahmoodpour M, Kiasari BA, Karimi M, Abroshan A, Shamshirian D, Hosseinalizadeh H, et al.. Paper-Based Biosensors As Point-Of-Care Diagnostic Devices for the Detection of Cancers: A Review of Innovative Techniques and Clinical Applications. Frontiers in Oncology. 2023;13():-.
BibTex	@article{ author = {Mahmoodpour M and Kiasari BA and Karimi M and Abroshan A and Shamshirian D and Hosseinalizadeh H and Delavari A and Mirzei H}, title = {Paper-Based Biosensors As Point-Of-Care Diagnostic Devices for the Detection of Cancers: A Review of Innovative Techniques and Clinical Applications}, journal = {Frontiers in Oncology}, volume = {13}, number = {}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Mahmoodpour M AU - Kiasari BA AU - Karimi M AU - Abroshan A AU - Shamshirian D AU - Hosseinalizadeh H AU - Delavari A AU - Mirzei H TI - Paper-Based Biosensors As Point-Of-Care Diagnostic Devices for the Detection of Cancers: A Review of Innovative Techniques and Clinical Applications JO - Frontiers in Oncology VL - 13 IS - SP - EP - PY - 2023 ER -

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