Extracellular Vesicles Biogenesis, Isolation, Manipulation and Genetic Engineering for Potential in Vitro and in Vivo Therapeutics: An Overview

Extracellular Vesicles Biogenesis, Isolation, Manipulation and Genetic Engineering for Potential in Vitro and in Vivo Therapeutics: An Overview Publisher

Hadizadeh N¹ ; Bagheri D² ; Shamsara M³ ; Hamblin MR⁴ ; Farmany A⁵ ; Xu M^{6, 7} ; Liang Z⁶ ; Razi F⁸ ; Hashemi E^{3, 6, 8}

Show Affiliations

1. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Molecular Genetics, Tarbiat Modares University, Tehran, Iran
3. Department of Animal Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran
4. Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States
5. Dental Research Centre and Dental Implant Research Centre, Hamadan University of Medical Sciences, Hamadan, Iran
6. Shenzhen Bay Laboratory, Institute of Molecular Physiology, Shenzhen, China
7. School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China
8. Metabolic Disorders Research Center, Endocrinology and Metabolism Molecularâ€”Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Frontiers in Bioengineering and Biotechnology Published:2022

Abstract

The main goals of medicine consist of early detection and effective treatment of different diseases. In this regard, the rise of exosomes as carriers of natural biomarkers has recently attracted a lot of attention and managed to shed more light on the future of early disease diagnosis methods. Here, exosome biogenesis, its role as a biomarker in metabolic disorders, and recent advances in state-of-art technologies for exosome detection and isolation will be reviewed along with future research directions and challenges regarding the manipulation and genetic engineering of exosomes for potential in vitro and in vivo disease diagnosis approaches. Copyright © 2022 Hadizadeh, Bagheri, Shamsara, Hamblin, Farmany, Xu, Liang, Razi and Hashemi.

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Style	Citing Format
MLA	Hadizadeh N, et al.. "Extracellular Vesicles Biogenesis, Isolation, Manipulation and Genetic Engineering for Potential in Vitro and in Vivo Therapeutics: An Overview." Frontiers in Bioengineering and Biotechnology, vol. 10, no. , 2022, pp. -.
APA	Hadizadeh N, Bagheri D, Shamsara M, Hamblin MR, Farmany A, Xu M, Liang Z, Razi F, Hashemi E (2022). Extracellular Vesicles Biogenesis, Isolation, Manipulation and Genetic Engineering for Potential in Vitro and in Vivo Therapeutics: An Overview. Frontiers in Bioengineering and Biotechnology, 10(), -.
Chicago	Hadizadeh N, Bagheri D, Shamsara M, Hamblin MR, Farmany A, Xu M, Liang Z, Razi F, Hashemi E. "Extracellular Vesicles Biogenesis, Isolation, Manipulation and Genetic Engineering for Potential in Vitro and in Vivo Therapeutics: An Overview." Frontiers in Bioengineering and Biotechnology 10, no. (2022): -.
Harvard	Hadizadeh N et al. (2022) 'Extracellular Vesicles Biogenesis, Isolation, Manipulation and Genetic Engineering for Potential in Vitro and in Vivo Therapeutics: An Overview', Frontiers in Bioengineering and Biotechnology, 10(), pp. -.
Vancouver	Hadizadeh N, Bagheri D, Shamsara M, Hamblin MR, Farmany A, Xu M, et al.. Extracellular Vesicles Biogenesis, Isolation, Manipulation and Genetic Engineering for Potential in Vitro and in Vivo Therapeutics: An Overview. Frontiers in Bioengineering and Biotechnology. 2022;10():-.
BibTex	@article{ author = {Hadizadeh N and Bagheri D and Shamsara M and Hamblin MR and Farmany A and Xu M and Liang Z and Razi F and Hashemi E}, title = {Extracellular Vesicles Biogenesis, Isolation, Manipulation and Genetic Engineering for Potential in Vitro and in Vivo Therapeutics: An Overview}, journal = {Frontiers in Bioengineering and Biotechnology}, volume = {10}, number = {}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Hadizadeh N AU - Bagheri D AU - Shamsara M AU - Hamblin MR AU - Farmany A AU - Xu M AU - Liang Z AU - Razi F AU - Hashemi E TI - Extracellular Vesicles Biogenesis, Isolation, Manipulation and Genetic Engineering for Potential in Vitro and in Vivo Therapeutics: An Overview JO - Frontiers in Bioengineering and Biotechnology VL - 10 IS - SP - EP - PY - 2022 ER -

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