Synthesis and Characterization of Polyhedral Oligomeric Titanized Silsesquioxane: A New Biocompatible Cage Like Molecule for Biomedical Application

Synthesis and Characterization of Polyhedral Oligomeric Titanized Silsesquioxane: A New Biocompatible Cage Like Molecule for Biomedical Application Publisher Pubmed

Yahyaei H¹ ; Mohseni M¹ ; Ghanbari H² ; Messori M³

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1. Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, P.O. Box 15875-4413, Tehran, Iran
2. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran
3. Dipartimento di Ingegneria 'Enzo Ferrari', Universita di Modena e Reggio Emilia, Modena, Italy

Source: Materials Science and Engineering C Published:2016

Abstract

Organic-inorganic hybrid materials have shown improved properties to be used as biocompatible coating in biomedical applications. Polyhedral oligomeric silsesquioxane (POSS) containing coatings are among hybrid materials showing promising properties for these applications. In this work an open cage POSS has been reacted with a titanium alkoxide to end cap the POSS molecule with titanium atom to obtain a so called polyhedral oligomeric metalized silsesquioxane (POMS). The synthesized POMS was characterized by FTIR, RAMAN and UV-visible spectroscopy as well as 29Si NMR and matrix assisted laser desorption/ionization time-of-flight (MALDI-TOF) techniques. Appearance of peaks at 920 cm- 1 in FTIR and 491 cm- 1 and 1083 cm- 1 in Raman spectra confirmed Si-O-Ti linkage formation. It was also demonstrated that POMS was in a monomeric form. To evaluate the biocompatibility of hybrids films, pristine POSS and synthesized POMS were used in synthesis of a polycarbonate urethane polymer. Results revealed that POMS containing hybrid, not only had notable thermal and mechanical stability compared to POSS containing one, as demonstrated by DSC and DMTA analysis, they also showed controlled surface properties in such a manner that hydrophobicity and biocompatibility were both reachable to give rise to improved cell viability in presence of human umbilical vein endothelial cells (HUVEC) and MRC-5 cells. © 2015 Elsevier B.V. All rights reserved.

2. Development of Novel Biocompatible Hybrid Nanocomposites Based on Polyurethane-Silica Prepared by Sol Gel Process, Materials Science and Engineering C (2016)

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Hossein Ghanbari (2)

Style	Citing Format
MLA	Yahyaei H, et al.. "Synthesis and Characterization of Polyhedral Oligomeric Titanized Silsesquioxane: A New Biocompatible Cage Like Molecule for Biomedical Application." Materials Science and Engineering C, vol. 61, no. , 2016, pp. 293-300.
APA	Yahyaei H, Mohseni M, Ghanbari H, Messori M (2016). Synthesis and Characterization of Polyhedral Oligomeric Titanized Silsesquioxane: A New Biocompatible Cage Like Molecule for Biomedical Application. Materials Science and Engineering C, 61(), 293-300.
Chicago	Yahyaei H, Mohseni M, Ghanbari H, Messori M. "Synthesis and Characterization of Polyhedral Oligomeric Titanized Silsesquioxane: A New Biocompatible Cage Like Molecule for Biomedical Application." Materials Science and Engineering C 61, no. (2016): 293-300.
Harvard	Yahyaei H et al. (2016) 'Synthesis and Characterization of Polyhedral Oligomeric Titanized Silsesquioxane: A New Biocompatible Cage Like Molecule for Biomedical Application', Materials Science and Engineering C, 61(), pp. 293-300.
Vancouver	Yahyaei H, Mohseni M, Ghanbari H, Messori M. Synthesis and Characterization of Polyhedral Oligomeric Titanized Silsesquioxane: A New Biocompatible Cage Like Molecule for Biomedical Application. Materials Science and Engineering C. 2016;61():293-300.
BibTex	@article{ author = {Yahyaei H and Mohseni M and Ghanbari H and Messori M}, title = {Synthesis and Characterization of Polyhedral Oligomeric Titanized Silsesquioxane: A New Biocompatible Cage Like Molecule for Biomedical Application}, journal = {Materials Science and Engineering C}, volume = {61}, number = {}, pages = {293-300}, year = {2016} }
RIS	TY - JOUR AU - Yahyaei H AU - Mohseni M AU - Ghanbari H AU - Messori M TI - Synthesis and Characterization of Polyhedral Oligomeric Titanized Silsesquioxane: A New Biocompatible Cage Like Molecule for Biomedical Application JO - Materials Science and Engineering C VL - 61 IS - SP - 293 EP - 300 PY - 2016 ER -

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