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Practice Guideline on Prevention, Diagnosis, and Treatment of Rhino-Orbito-Cerebral Mucormycosis in the Covid-19 Area: A Consensus of Iranian Experts Publisher



Pakdel F1 ; Mardani M2 ; Salehi M3 ; Khodavaisy S4 ; Tabari A5
Authors
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Authors Affiliations
  1. 1. Department of Oculo-Facial Plastic Surgery, Department of Ophthalmology, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Infectious Disease, School of Medicine, Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Department of infectious diseases and Tropical Medicine, Imam Khomeini Hospital complex, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Otorhinolaryngology, Imam Khomeini Hospital complex, Tehran University of Medical Sciences, Tehran, Iran

Source: Archives of Clinical Infectious Diseases Published:2022


Abstract

Context: The current pandemic of COVID-19 affected all people of the world. Evidence Acquisition: Most complications of SARS-CoV-2 are causally related to severe pneumonia due to host immune response in the form of a cytokine storm. The other causes of an increased mortality rate among COVID-19 patients are secondary infections. Results: Mucormycosis is a life-threatening infection that gained much attention in the ongoing COVID-19 pandemic. A rise in the frequency of COVID-19-associated mucormycosis (CAM) occurred in 2020 and 2021. Overall, mortality of CAM has been reported as 54%-75%. Conclusions: Although awareness of the disease has increased among treating physicians, disease-associated morbidity and mortality are still high. The guideline is intended to serve as a reference to prevent mucormycosis in COVID-19 patients and help health-care providers choose diagnostic and treatment methods for the best management of CAM cases. © 2022, Author(s).
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