Bacillus Coagulans T4 and Lactobacillus Paracasei Td3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57bl/6J Mice

Bacillus Coagulans T4 and Lactobacillus Paracasei Td3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57bl/6J Mice Publisher

Shams M¹ ; Esmaeili F² ; Sadeghi S¹ ; Shanakibavarsad M³ ; Ebrahimi SSS² ; Hashemnia SMR² ; Tajabadiebrahimi M⁴ ; Emamgholipour S² ; Shanaki M¹

Show Affiliations

1. Department of Medical Laboratory Sciences, School of Allied Medical Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2. Department of Clinical Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, CA, United States
4. Department of Biology, Tehran Central Branch, Islamic Azad University, Tehran, Iran

Source: Iranian Journal of Pharmaceutical Research Published:2023

Abstract

Background: This study aims to investigate the effects of Bacillus coagulans T4 and Lactobacillus paracasei TD3 probiotics on skeletal muscle inflammation and oxidative stress in C57BL/6J mice fed a high-fat diet (HFD). Methods: Probiotics B. coagulans T4, and L. paracasei TD3 were administered to male C57BL/6J mice fed with HFD. The gene expression of macrophage infiltration markers, inflammatory cytokines, and oxidative stress indicators in the muscle tissue was investigated. Results: Treatment with B. coagulans T4 and L. paracasei TD3 reduced macrophage infiltration, accompanied by a decrease in the expression of monocyte chemoattractant protein-1 (MCP-1) and an increase in the expression of interleukin (IL)-10. On the other hand, L. paracasei TD3 decreased malondialdehyde (MDA) while B. coagulans T4 decreased carbonyl and increased catalase activity. Conclusions: Treatment with probiotics B. coagulans T4 and L. paracasei TD3 partially ameliorated obesity-induced skeletal muscle inflammation in HFD-fed mice. © 2023, Author(s).

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Style	Citing Format
MLA	Shams M, et al.. "Bacillus Coagulans T4 and Lactobacillus Paracasei Td3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57bl/6J Mice." Iranian Journal of Pharmaceutical Research, vol. 22, no. 1, 2023, pp. -.
APA	Shams M, Esmaeili F, Sadeghi S, Shanakibavarsad M, Ebrahimi SSS, Hashemnia SMR, Tajabadiebrahimi M, Emamgholipour S, Shanaki M (2023). Bacillus Coagulans T4 and Lactobacillus Paracasei Td3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57bl/6J Mice. Iranian Journal of Pharmaceutical Research, 22(1), -.
Chicago	Shams M, Esmaeili F, Sadeghi S, Shanakibavarsad M, Ebrahimi SSS, Hashemnia SMR, Tajabadiebrahimi M, Emamgholipour S, Shanaki M. "Bacillus Coagulans T4 and Lactobacillus Paracasei Td3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57bl/6J Mice." Iranian Journal of Pharmaceutical Research 22, no. 1 (2023): -.
Harvard	Shams M et al. (2023) 'Bacillus Coagulans T4 and Lactobacillus Paracasei Td3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57bl/6J Mice', Iranian Journal of Pharmaceutical Research, 22(1), pp. -.
Vancouver	Shams M, Esmaeili F, Sadeghi S, Shanakibavarsad M, Ebrahimi SSS, Hashemnia SMR, et al.. Bacillus Coagulans T4 and Lactobacillus Paracasei Td3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57bl/6J Mice. Iranian Journal of Pharmaceutical Research. 2023;22(1):-.
BibTex	@article{ author = {Shams M and Esmaeili F and Sadeghi S and Shanakibavarsad M and Ebrahimi SSS and Hashemnia SMR and Tajabadiebrahimi M and Emamgholipour S and Shanaki M}, title = {Bacillus Coagulans T4 and Lactobacillus Paracasei Td3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57bl/6J Mice}, journal = {Iranian Journal of Pharmaceutical Research}, volume = {22}, number = {1}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Shams M AU - Esmaeili F AU - Sadeghi S AU - Shanakibavarsad M AU - Ebrahimi SSS AU - Hashemnia SMR AU - Tajabadiebrahimi M AU - Emamgholipour S AU - Shanaki M TI - Bacillus Coagulans T4 and Lactobacillus Paracasei Td3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57bl/6J Mice JO - Iranian Journal of Pharmaceutical Research VL - 22 IS - 1 SP - EP - PY - 2023 ER -

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