Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Liquid Biopsy and Its Significance on the Early Detection of Breast Cancer; [بیوپسی مایع و اهمیت آن در تشخیص زودهنگام سرطان پستان] Publisher



Hasannejad F1 ; Fazilat A1 ; Majidzadeh KA1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Genetics, Breast Cancer Research Center, ACECR, Motamed Cancer Institute, Tehran, Iran

Source: Iranian Journal of Breast Diseases Published:2024


Abstract

Introduction: Liquid biopsy is a novel diagnostic tool that investigates biological biomarkers within the blood and other body liquids in order to provide information about the genetics of the tumor and its treatment response. The current review study aimed to highlight the role of liquid biopsy in breast cancer and precision medicine. Methods: In the current review study, we attempted to evaluate the recent innovations in breast cancer diagnosis by investigating liquid biopsy biomarkers in related databases, including Scopus, Web of Science, PubMed, and Google Scholar, from 2018 to 2024. Results: The assessment of the published articles in this field revealed that the applications of biomarkers in liquid biopsy have a significant role in personalized medicines, highlighting their reliability for use in personalized medicine. Conclusion: The liquid biopsy biomarkers seem to be a promising approach in breast cancer early detection and remarkable reduction of mortality caused by this disease in the near future. © 2024 Hasannejad et al.
Related Docs
View other Related Docs
1. Recent Advancements in Polyaniline-Based Biosensors for Diagnosis of Cancers: A Comprehensive Review, TrAC - Trends in Analytical Chemistry (2024)
2. Salivary Biomarkers in Breast Cancer Diagnosis: A Systematic Review and Diagnostic Meta-Analysis, Cancer Medicine (2022)
3. Tumor-Educated Platelets, Clinica Chimica Acta (2024)
4. A Review of Salivary Biomarkers in Breast Cancer, Current Women's Health Reviews (2023)
5. Comparison of Machine Learning Models for Classification of Breast Cancer Risk Based on Clinical Data, Cancer Reports (2025)
6. Critical Involvement of Circular Rnas in Virus-Associated Cancers, Genes and Diseases (2023)
7. Global Research Trends on Colorectal Cancer (2014-2023): A Scientometric and Visualized Study, Archives of Iranian Medicine (2024)
8. Development of Multifunctional Mno2-Based Nanoplatforms for Hypoxia Modulation/T1-Weighted Mri/ Optical Biosensing and Targeted Drug Delivery, Journal of Drug Delivery Science and Technology (2024)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (8)
Bagher Larijani (8)
Other Related Docs
9. Curcumin and Its Novel Formulations for the Treatment of Hepatocellular Carcinoma: New Trends and Future Perspectives in Cancer Therapy, Journal of Functional Foods (2023)
10. Association of Imaging and Pathological Findings of Breast Cancer in Very Young Women: Report of a Twenty-Year Retrospective Study, Clinical Imaging (2024)
11. Trends in Global, Regional, and National Burden and Quality of Care Index for Liver Cancer by Cause From Global Burden of Disease 1990-2019, Hepatology Communications (2022)
12. Cigarettes and Waterpipe Use and Risk of Colorectal Cancer in Iran: The Iropican Study, European Journal of Cancer Prevention (2025)
13. Systematic Review and Meta-Analysis of the Association Between the Use of Sglt2 Inhibitors and Hepatocellular Carcinoma, Immunopathologia Persa (2025)
14. Salivary Noncoding Rna in the Diagnosis of Pancreatic Cancer: Systematic Review and Meta-Analysis, European Journal of Clinical Investigation (2022)
15. Circulating Circular Rna Adam9 a Potential Biomarker for Human Colorectal Cancer, Gene Reports (2022)
16. Deciphering the Oncogenic Landscape: Unveiling the Molecular Machinery and Clinical Significance of Lncrna Tmpo-As1 in Human Cancers, Pathology Research and Practice (2024)
17. Advances in Therapeutic Targeting of Immune Checkpoints Receptors Within the Cd96-Tigit Axis: Clinical Implications and Future Perspectives, Expert Review of Clinical Immunology (2022)
18. The Global Incidence, Mortality, and Burden of Breast Cancer in 2019: Correlation With Smoking, Drinking, and Drug Use, Frontiers in Oncology (2022)
19. Trends in Incidence of Prostate Cancer in Iran and Its 31 Provinces During 2003 - 2016, International Journal of Cancer Management (2023)
20. A Crosstalk Between Epigenetic Modulations and Non-Alcoholic Fatty Liver Disease Progression, Pathology Research and Practice (2023)
21. An Update to Experimental and Clinical Aspects of Tumor-Associated Macrophages in Cancer Development: Hopes and Pitfalls, Clinical and Experimental Medicine (2024)
22. Burden of Breast Cancer and Attributable Risk Factors in the North Africa and Middle East Region, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019, Frontiers in Oncology (2023)
23. Direct and Indirect Medical Costs of Bladder Cancer in Iran, Cost Effectiveness and Resource Allocation (2023)
24. Immunotherapeutic Targets in Non-Small Cell Lung Cancer, Immunology (2023)
25. Burden of Thyroid Cancer in North Africa and Middle East 1990–2019, Frontiers in Oncology (2022)
26. The Critical Role of Circular Rnas in Drug Resistance in Gastrointestinal Cancers, Medical Oncology (2023)
27. Using a Social Marketing Approach to Increase the Pap-Smear Test Uptake: Randomized Controlled Trial Among Women Residing in Urban Region, BMC Women's Health (2025)
28. Evaluation of Cstb and Dmbt1 Expression in Saliva of Gastric Cancer Patients and Controls, BMC Cancer (2022)
29. The Expression of Sox10 and Its Value for Predicting Tumor Biological Behaviors in Patients Suffering Gastric Adenocarcinoma, Cross Sectional Study, International Journal of Surgery Open (2022)
30. Principles of Pharmacogenomics and Pharmacogenetics, Precision Medicine in Clinical Practice (2022)
31. Physical and Functional Evaluations in Oncological Patients Elective to Medium and Large Operations, Supportive Care in Cancer (2023)
32. Sleep Disturbance and Gastrointestinal Cancer Risk: A Literature Review, Journal of Investigative Medicine (2023)
33. Development and Clinical Application of Tumor-Derived Exosomes in Patients With Cancer, Current Stem Cell Research and Therapy (2022)
34. Nanotechnology-Assisted Lung Cancer Diagnosis: Biomarkers and Imaging, Journal of Nanoparticle Research (2025)
35. Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 a Systematic Analysis for the Global Burden of Disease Study 2019, JAMA Oncology (2022)
36. National and Subnational Burden of Female and Male Breast Cancer and Risk Factors in Iran From 1990 to 2019: Results From the Global Burden of Disease Study 2019, Breast Cancer Research (2023)
37. The Burden of Prostate Cancer in North Africa and Middle East, 1990–2019: Findings From the Global Burden of Disease Study, Frontiers in Oncology (2022)
38. The Role of Her2 Alterations in Clinicopathological and Molecular Characteristics of Breast Cancer and Her2-Targeted Therapies: A Comprehensive Review, Medical Oncology (2022)
39. Anti-Cd20 Antibody Treatment for B-Cell Malignancies, Resistance to Anti-CD20 Antibodies and approaches for their Reversal: Volume 2 (2023)
40. Recent Advances in Regenerative Medicine Strategies for Cancer Treatment, Biomedicine and Pharmacotherapy (2021)
41. Diagnosis of Cervical Cancer and Pre-Cancerous Lesions by Artificial Intelligence: A Systematic Review, Diagnostics (2022)
42. The Significance of Exosomal Non-Coding Rnas (Ncrnas) in the Metastasis of Colorectal Cancer and Development of Therapy Resistance, Gene (2025)
43. Molecular Docking As a Therapeutic Approach for Targeting Cancer Stem Cell Metabolic Processes, Frontiers in Pharmacology (2022)
44. Functions, Mechanisms, and Clinical Applications of Lncrna Linc00857 in Cancer Pathogenesis, Human Cell (2023)
45. The Role of Pirnas in Predicting and Prognosing in Cancer: A Focus on Pirna-823 (A Systematic Review and Meta-Analysis), BMC Cancer (2024)
46. Toxic Mechanisms of Cadmium and Exposure As a Risk Factor for Oral and Gastrointestinal Carcinomas, Human and Experimental Toxicology (2023)
47. Building a Cancer Biobank in a Low-Resource Setting in Northern Iran: The Golestan Cancer Biobank, Archives of Iranian Medicine (2021)
48. The Epidemiology of Brain and Spinal Cord Tumors, Advances in Experimental Medicine and Biology (2023)
49. Global, Regional and National Burden of Bladder Cancer and Its Attributable Risk Factors in 204 Countries and Territories, 1990-2019: A Systematic Analysis for the Global Burden of Disease Study 2019, BMJ Global Health (2021)
50. Trim14 and Trim29 As Potential Tumor Markers for Breast Cancer Diagnosis; [14Trim و 29Trim به عنوان تومور مارکرهای بالقوه برای تشخیص ], Iranian Journal of Breast Diseases (2024)