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Lavender and Geranium Essential Oil-Loaded Nanogels With Promising Repellent and Antibacterial Effects Publisher



Saneidehkordi A1, 2 ; Abdollahi A3 ; Montaseri Z4 ; Safari M5 ; Rostami Chaijan M6 ; Osanloo M7
Authors
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Authors Affiliations
  1. 1. Department of Biology and Control of Disease Vectors, School of Health, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
  2. 2. Infectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
  3. 3. Department of Microbiology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran
  4. 4. Department of Infectious Diseases, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran
  5. 5. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Persian Medicine, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran
  7. 7. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran

Source: Psyche: Journal of Entomology Published:2023


Abstract

Malaria and bacterial infections remain a life-threatening disease with a significant global impact. This study aimed to develop nanogels (NGs) of lavender (Lavandula angustifolia Mill.) and geranium (Pelargonium graveolens L'Her.) essential oils (EOs) with promising repellent and antibacterial effects. The NGs were formulated using a nanoemulsion-based gel approach; nanoemulsion droplet sizes and zeta potentials were obtained as 146 ± 7 and 106 ± 6 nm and -23.2 ± 0.7 and -17.4 ± 1 mV, respectively. The ATR-FTIR analysis confirmed the successful loading of EOs in NGs. Repellent bioassays conducted on Anopheles stephensi Liston. mosquitoes demonstrated that geranium NG (140 min) was as effective as DEET (140 min), a widely used repellent. Antibacterial tests showed that the nanogels effectively reduced bacterial growth, with the geranium NG exhibiting over 90% reduction against Escherichia coli Migula. The lavender NG displayed higher efficacy against Staphylococcus aureus Rosenbach. These findings highlighted the potential of nanogels containing EOs as promising repellents and antibacterial agents, offering a sustainable and eco-friendly approach for vector control and bacterial infections. © 2023 Alireza Sanei-Dehkordi et al.