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Inflammatory Cytokines and Type 2 Diabetes



Jokar MH1 ; Sedighi S1 ; Mohamadkhani A2 ; Moradzadeh M1
Authors
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Authors Affiliations
  1. 1. Golestan Rheumatology Research Center, Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran
  2. 2. Liver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Koomesh Published:2020

Abstract

Inflammatory cytokines increase in patients with type 2 diabetes (T2D) and metabolic syndrome. This review focuses on inflammatory cytokines such as C-reactive protein (CRP), tumor necrosis factor (TNF-a), and adiponectin, a cytokine produced by adipose tissue and associated with insulin sensitivity. Despite the major role of cytokines in the development of T2D, in the case of adiponectin still is a matter of debate as the best strategy to change proper inflammatory response. © 2020, Semnan University of Medical Sciences. All rights reserved.
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