Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Factors Associated With Mortality in Hospitalized Cardiovascular Disease Patients Infected With Covid-19 Publisher Pubmed



Alizadehsani R1 ; Eskandarian R2 ; Behjati M3 ; Zahmatkesh M2 ; Roshanzamir M4 ; Izadi NH5 ; Shoeibi A6, 7 ; Haddadi A8 ; Khozeimeh F1 ; Sani FA9 ; Sani ZA10 ; Roshanzamir Z11 ; Khosravi A1 ; Nahavandi S1 Show All Authors
Authors
  1. Alizadehsani R1
  2. Eskandarian R2
  3. Behjati M3
  4. Zahmatkesh M2
  5. Roshanzamir M4
  6. Izadi NH5
  7. Shoeibi A6, 7
  8. Haddadi A8
  9. Khozeimeh F1
  10. Sani FA9
  11. Sani ZA10
  12. Roshanzamir Z11
  13. Khosravi A1
  14. Nahavandi S1
  15. Sarrafzadegan N12, 13
  16. Islam SMS14, 15, 16
Show Affiliations
Authors Affiliations
  1. 1. Institute for Intelligent Systems Research and Innovation (IISRI), Deakin University, Geelong, Australia
  2. 2. Internal Medicine Research Center, Semnan University of Medical Sciences, Semnan, Iran
  3. 3. Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Engineering, Fasa University, Fars, Fasa, Iran
  5. 5. Department of Electrical and Computer Engineering, Isfahan University of Technology, Isfahan, Iran
  6. 6. Computer Engineering Department, Ferdowsi University of Mashhad, Mashhad, Iran
  7. 7. Faculty of Electrical and Computer Engineering, Biomedical Data Acquisition Lab, K. N. Toosi University of Technology, Tehran, Iran
  8. 8. Department of Biology, Faculy of Basic Sciences, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
  9. 9. Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran
  10. 10. Department of Cardiac MRI, Omid Hospital, Tehran, Iran
  11. 11. Pediatric Respiratory and Sleep Medicine Research Center, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  12. 12. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  13. 13. Faculty of Medicine, SPPH, University of British Columbia, Vancouver, BC, Canada
  14. 14. Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, Australia
  15. 15. Cardiovascular Division, The George Institute for Global Health, Newtown, Australia
  16. 16. Sydney Medical School, University of Sydney, Camperdown, Australia

Source: Immunity# Inflammation and Disease Published:2022


Abstract

Introduction: To reduce mortality in hospitalized patients with COVID-19 and cardiovascular disease (CVD), it is necessary to understand the relationship between patient's symptoms, risk factors, and comorbidities with their mortality rate. To the best of our knowledge, this paper is the first which take into account the determinants like risk factors, symptoms, and comorbidities leading to mortality in CVD patients who are hospitalized with COVID-19. Methods: This study was conducted on 660 hospitalized patients with CVD and COVID-19 recruited between January 2020 and January 2021 in Iran. All patients were diagnosed with the previous history of CVD like angina, myocardial infarction, heart failure, cardiomyopathy, abnormal heart rhythms, and congenital heart disease before they were hospitalized for COVID-19. We collected data on patient's signs and symptoms, clinical and paraclinical examinations, and any underlying comorbidities. t test was used to determine the significant difference between the two deceased and alive groups. In addition, the relation between pairs of symptoms and pairs of comorbidities has been determined via correlation computation. Results: Our findings suggest that signs and symptoms such as fever, cough, myalgia, chest pain, chills, abdominal pain, nausea, vomiting, diarrhea, and anorexia had no impact on patients' mortality. There was a significant correlation between COVID-19 cardiovascular patients' mortality rate and symptoms such as headache, loss of consciousness (LOC), oxygen saturation less than 93%, and need for mechanical ventilation. Conclusions: Our results might help physicians identify early symptoms, comorbidities, and risk factors related to mortality in CVD patients hospitalized for COVID-19. © 2021 The Authors. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd.
Other Related Docs
12. Coagulopathy: Another Side Effect of Coronavirus Infection, Journal of Cardiovascular and Thoracic Research (2021)
18. Case Fatality Rate of Covid-19: A Systematic Review and Meta-Analysis, Journal of Preventive Medicine and Hygiene (2021)
19. Sars-Cov-2 and Acute Cerebrovascular Events: An Overview, Journal of Clinical Medicine (2021)
22. Factors Associated With the Poor Outcomes in Diabetic Patients With Covid-19, Journal of Diabetes and Metabolic Disorders (2020)
25. Critical Complications of Covid-19: A Descriptive Meta-Analysis Study, Reviews in Cardiovascular Medicine (2020)
30. Predictors of Mortality in Patients With Covid-19–A Systematic Review, European Journal of Integrative Medicine (2020)