Tobacco Consumption, Opium Use, Alcohol Drinking and the Risk of Esophageal Cancer in North Khorasan, Iran Publisher



Pournaghi SJ¹ ; Hojjat SK² ; Barazandeh Noveyri F¹ ; Tavakkoli Ghouchani H³ ; Ahmadi A⁴ ; Hamedi A^{5, 9} ; Rahimi J⁶ ; Mohamaddoust H⁷ ; Lashkardoost H⁸ Show Affiliations
Source: Journal of Substance Use Published:2019

Abstract

Background: There are some unique epidemiological characteristics of esophageal cancer in Iran. The objective of this study was finding the association between tobacco, substance and alcohol using with the risk of esophageal cancer in North Khorasan, Iran. Methods: This Case-Control study was carried out on 96 patients with esophageal cancer and 187 controls. Controls were matched to cases by age and sex. Data were collected through structured interview. Data were analyzed by using chi-square test, T-test and logistic regression, in Stata software version 12. Results: Our findings show Hookah smoking [OR = 6.1(CI95%:1.2–13.1)] and opium consumption [OR = 2.1(CI95%:1.2–3.5)] were associated with esophageal cancer. Cigarette and pipe smoking, age of onset of smoking, duration of smoking, number of smoking per day, leaving history of smoking, years of leaving smoking, drug withdrawal, number of times of drug withdrawal, a history of drug relapse, alcohol consumption and alcohol dose–response were not related to esophageal cancer. Conclusion: According to our results, hookah smoking and opium consumption enhance the risk of esophageal cancer in North Khorasan of Iran. We suggest appropriate planning to prevent the esophageal cancer in this district. © 2018, © 2018 Taylor & Francis Group, LLC.