Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Pars Cohort Study of Non-Communicable Diseases in Iran: Protocol and Preliminary Results Publisher Pubmed



Gandomkar A1 ; Poustchi H2 ; Moini M3 ; Moghadami M1 ; Imanieh H1 ; Fattahi MR3 ; Ayatollahi SMT4 ; Sagheb MM5 ; Anushiravani A6 ; Mortazavi R6 ; Sepanlou SG7 ; Malekzadeh R1, 8
Authors
Show Affiliations
Authors Affiliations
  1. 1. Non-Communicable Disease Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  2. 2. Liver, Pancreatic, and Biliary Diseases Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Department of Biostatistics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  5. 5. Nephrology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  6. 6. Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  7. 7. Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Tehran University of Medical Sciences, Tehran, Iran

Source: International Journal of Public Health Published:2017


Abstract

Objectives: The pars cohort study (PCS) is a 10-year cohort study aiming to investigate the burden and the major risk factors of non-communicable diseases, and to establish a setting to launch interventions for prevention of these diseases and controlling their risk factors. Methods: All inhabitants of Valashahr district in South of Iran, aged 40–75 years, were invited to undergo interviews and physical examination, and to provide biological samples. A total of 9264 invitees accepted to participate in the study (95 % participation rate) and were recruited from 2012 to 2014. Active follow-up was also carried out after 12 months. Results: About 46 % of participants were male and 54 % were female. About 14.0 % of the participants were current smokers and 8.4 % were ever opium users. The prevalence of overweight and obesity were 37.3 and 18.2 %, respectively. The prevalence of hypertension was 26.9 %. A total of 49 participants died during a median follow-up of one year. Conclusions: PCS with its large scale and wealth of socio-economic and medical data can be a unique platform for studying the etiology of non-communicable diseases and effective interventions in Iran. © 2016, Swiss School of Public Health (SSPH+).
Related Docs
View other Related Docs
1. Individual and Combined Effects of Environmental Risk Factors for Esophageal Cancer Based on Results From the Golestan Cohort Study, Gastroenterology (2019)
2. Oral Health and Risk of Upper Gastrointestinal Cancers in a Large Prospective Study From a High-Risk Region: Golestan Cohort Study, Cancer Prevention Research (2021)
3. The Application of Six Dietary Scores to a Middle Eastern Population: A Comparative Analysis of Mortality in a Prospective Study, European Journal of Epidemiology (2019)
4. Cancer Incidence in the East Azerbaijan Province of Iran in 2015-2016: Results of a Population-Based Cancer Registry, BMC Public Health (2018)
5. Mortality From Respiratory Diseases Associated With Opium Use: A Population-Based Cohort Study, Thorax (2017)
6. Major Dietary Protein Sources in Relation to Pancreatic Cancer: A Large Prospective Study, Archives of Iranian Medicine (2016)
7. Association Between Prediagnostic Risk Factors and Survival After Colorectal Cancer Diagnosis in Golesten Cohort Study, Scientific Reports (2025)
8. The Combined Effects of Healthy Lifestyle Behaviors on All-Cause Mortality: The Golestan Cohort Study, Archives of Iranian Medicine (2016)
Experts (# of related papers)
View all Related Experts
Hossein Poustchi (109)
Reza Malekzadeh (105)
Other Related Docs
9. Long-Term Opiate Use and Risk of Cardiovascular Mortality: Results From the Golestan Cohort Study, European Journal of Preventive Cardiology (2021)
10. Opium Use and Risk of Pancreatic Cancer: A Prospective Cohort Study, Cancer Epidemiology Biomarkers and Prevention (2018)
11. Diet Quality and Subsequent Incidence of Upper Gastrointestinal Cancers: Results From the Golestan Cohort Study, Archives of Iranian Medicine (2023)
12. The Iranian Study of Opium and Cancer (Iropican): Rationale, Design, and Initial Findings, Archives of Iranian Medicine (2021)
13. Multimorbidity: Epidemiology and Risk Factors in the Golestan Cohort Study, Iran a Cross-Sectional Analysis, Medicine (United States) (2016)
14. Food Preparation Methods, Drinking Water Source, and Esophageal Squamous Cell Carcinoma in the High-Risk Area of Golestan, Northeast Iran, European Journal of Cancer Prevention (2016)
15. Joint Effect of Diabetes and Opiate Use on All-Cause and Cause-Specific Mortality: The Golestan Cohort Study, International Journal of Epidemiology (2021)
16. Adherence to the Dietary Approaches to Stop Hypertension (Dash) Diet and Risk of Total and Cause-Specific Mortality: Results From the Golestan Cohort Study, International Journal of Epidemiology (2019)
17. Dairy Food Intake and All-Cause, Cardiovascular Disease, and Cancer Mortality: The Golestan Cohort Study, American Journal of Epidemiology (2017)
18. Opium Use, Cigarette Smoking, and Alcohol Consumption in Relation to Pancreatic Cancer, Medicine (United States) (2016)
19. Hazards of Cigarettes, Smokeless Tobacco and Waterpipe in a Middle Eastern Population: A Cohort Study of 50 000 Individuals From Iran, Tobacco Control (2017)
20. Opium Use and Subsequent Incidence of Cancer: Results From the Golestan Cohort Study, The Lancet Global Health (2020)
21. Opiate and Tobacco Use and Exposure to Carcinogens and Toxicants in the Golestan Cohort Study, Cancer Epidemiology Biomarkers and Prevention (2020)
22. Causes of Premature Death and Their Associated Risk Factors in the Golestan Cohort Study, Iran, BMJ Open (2018)
23. Population Attributable Fraction of Dietary Risk Factors for Cancer Mortality With a Focus on Gastrointestinal Cancers in a Population Based Cohort Study, Scientific Reports (2025)
24. Association Between Incident Type 2 Diabetes and Opium Use: Mediation by Body Mass and Adiposity, American Journal of Epidemiology (2023)
25. Dental Health and Lung Cancer Risk in the Golestan Cohort Study, BMC Cancer (2024)
26. Fifty Years of Research and One Conclusion: Opium Causes Cancer, Archives of Iranian Medicine (2020)
27. Multiplex H. Pylori Serology and Risk of Gastric Cardia and Noncardia Adenocarcinomas, Cancer Research (2015)
28. Prospective Epidemiological Research Studies in Iran (The Persian Cohort Study): Rationale, Objectives, and Design, American Journal of Epidemiology (2018)
29. Dietary Advanced Glycation End Products and Risk of Overall and Cause-Specific Mortality: Results From the Golestan Cohort Study, International Journal of Environmental Research and Public Health (2023)
30. Dietary Protein Sources and All-Cause and Cause-Specific Mortality: The Golestan Cohort Study in Iran, American Journal of Preventive Medicine (2017)
31. Oral Health and Mortality in the Golestan Cohort Study, International Journal of Epidemiology (2017)
32. Building Cancer Registries in a Lower Resource Setting: The 10-Year Experience of Golestan, Northern Iran, Cancer Epidemiology (2018)
33. Trends in the Incidence of Stomach Cancer in Golestan Province, a High-Risk Area in Northern Iran, 2004-2016, Archives of Iranian Medicine (2020)
34. Prevalence and Determinants of Chronic Kidney Disease in Northeast of Iran: Results of the Golestan Cohort Study, PLoS ONE (2017)
35. Hypertension and Mortality in the Golestan Cohort Study: A Prospective Study of 50 000 Adults in Iran, Journal of Human Hypertension (2016)
36. The Clinical Performance of an Office-Based Risk Scoring System for Fatal Cardiovascular Diseases in North-East of Iran, PLoS ONE (2015)
37. Prevalence and Determinants of Opioid Use Disorder Among Long-Term Opiate Users in Golestan Cohort Study, BMC Psychiatry (2023)
38. Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study, Environmental Health Perspectives (2020)
39. Pre-Diagnostic Risk Factors for Brain Cancer Incidence and Survival: Insights From the Golestan Cohort Study, BMC Cancer (2025)
40. Does Opium Consumption Have Shared Impact on Atherosclerotic Cardiovascular Disease and Cancer?, Archives of Iranian Medicine (2022)
41. Cardiovascular Disease Mortality and Years of Life Lost Attributable to Non-Optimal Systolic Blood Pressure and Hypertension in Northeastern Iran, Archives of Iranian Medicine (2015)
42. Dietary Intake of Minerals and Risk of Esophageal Squamous Cell Carcinoma: Results From the Golestan Cohort Study, American Journal of Clinical Nutrition (2015)
43. The Marginal Causal Effect of Opium Consumption on the Upper Gastrointestinal Cancer Death Using Parametric G-Formula: An Analysis of 49,946 Cases in the Golestan Cohort Study, Iran, PLoS ONE (2021)
44. Prevalence and Clinical Outcomes of Common Bile Duct Dilation in Patients Who Use Opium, American Journal of the Medical Sciences (2018)
45. Survival Assessment and Pre-Diagnostic Risk Factors for Lung Cancer Incidence: Insights From the Golestan Cohort Study, PLoS ONE (2025)
46. Sensitivity of Self-Reported Opioid Use in Case-Control Studies: Healthy Individuals Versus Hospitalized Patients, PLoS ONE (2017)
47. The Persian Cohort: Providing the Evidence Needed for Healthcare Reform, Archives of Iranian Medicine (2017)
48. Mineral Intake and Cardiovascular Disease, Cancer, and All-Cause Mortality: Findings From the Golestan Cohort Study, Nutrients (2024)
49. The Global, Regional, and National Burden of Oesophageal Cancer and Its Attributable Risk Factors in 195 Countries and Territories, 1990-2017: A Systematic Analysis for the Global Burden of Disease Study 2017, The Lancet Gastroenterology and Hepatology (2020)
50. Household Fuel Use and Cardiovascular Disease Mortality, Circulation (2016)