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The Involvement of the Central Nervous System in Patients With Covid-19 Publisher Pubmed



Saleki K1 ; Banazadeh M1 ; Saghazadeh A1, 2 ; Rezaei N2, 3, 4
Authors
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Authors Affiliations
  1. 1. Systematic Review and Meta-analysis Expert Group, Universal Scientific Education and Research Network (USERN), Tehran, 14194, Iran
  2. 2. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Dr. Qarib St, Keshavarz Blvd, Tehran, 14194, Iran
  3. 3. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, 14194, Iran
  4. 4. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, 14194, Iran

Source: Reviews in the Neurosciences Published:2020


Abstract

Coronaviruses disease (COVID-19) has caused major outbreaks. A novel variant, SARS-CoV-2, is responsible for COVID-19 pandemic. Clinical presentations and pathological mechanisms of COVID-19 are broad. The respiratory aspect of the disease has been extensively researched. Emerging studies point out the possibility of the central nervous system (CNS) involvement by COVID-19. Here, we discuss the current evidence for CNS involvement in COVID-19 and highlight that the high pathogenicity of SARS-CoV-2 might be due to its neuroinvasive potential. © 2020 Walter de Gruyter GmbH, Berlin/Boston 2020.
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