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The Establishment of the Household Air Pollution Consortium (Hapco) Publisher



Klugman M1 ; Matsuo K2 ; White AJ3 ; Sadakane A4 ; Shu XO5 ; Lopezridaura R6 ; Shin A7 ; Tsuji I8 ; Malekzadeh R9 ; Noisel N10 ; Bhatti P11 ; Yang G12 ; Saito E13 ; Rahman S14 Show All Authors
Authors
  1. Klugman M1
  2. Matsuo K2
  3. White AJ3
  4. Sadakane A4
  5. Shu XO5
  6. Lopezridaura R6
  7. Shin A7
  8. Tsuji I8
  9. Malekzadeh R9
  10. Noisel N10
  11. Bhatti P11
  12. Yang G12
  13. Saito E13
  14. Rahman S14
  15. Hu W15
  16. Bassig B15
  17. Downward G16
  18. Vermeulen R16
  19. Xue X1
  20. Rohan T1
  21. Abe SK17
  22. Broet P10
  23. Grant EJ4
  24. Dummer TJB18
  25. Rothman N15
  26. Inoue M17
  27. Lajous M6, 19
  28. Yoo KY7
  29. Ito H2
  30. Sandler DP3
  31. Ashan H20
  32. Zheng W12
  33. Boffetta P21, 22
  34. Lan Q15
Show Affiliations
Authors Affiliations
  1. 1. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, 10461, NY, United States
  2. 2. Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, 464-8681, Japan
  3. 3. Epidemiology Branch, National Institute of Environmental Health Science, Research Triangle Park, 27709, NC, United States
  4. 4. Department of Epidemiology, Radiation Effects Research Foundation, Hiroshima, 732-0815, Japan
  5. 5. Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Vanderbilt University Medicine Center, Nashville, 37203-1738, TN, United States
  6. 6. National Institute of Public Health, Cuernavaca, Morelos, 62100, Mexico
  7. 7. Department of Preventative Medicine, Seoul National University College of Medicine, Seoul, 03080, South Korea
  8. 8. Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University Graduate School of Medicine, Miyagi, 980-8575, Japan
  9. 9. Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, 14117, Iran
  10. 10. CARTaGENE, Centre de Recherche du CHU Sainte-Justine, Montreal, H3T 1C5, QC, Canada
  11. 11. BC Cancer, Vancouver, V5Z 1L3, BC, Canada
  12. 12. Center for Health Services, Vanderbilt University School of Medicine, Nashville, 37203-1738, TN, United States
  13. 13. Division of Cancer Statistics and Integration, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, 104-0045, Japan
  14. 14. Department of Global Health Policy, Graduate School of Medicine, University of Tokyo, Tokyo, 113-8654, Japan
  15. 15. Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, 20892-7240, MD, United States
  16. 16. Institute for Risk Assessment Services, Utrecht University, Utrecht, 3508, Netherlands
  17. 17. Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, 104-0045, Japan
  18. 18. School of Population and Public Health, University of British Columbia, Vancouver, V6T 1Z3, BC, Canada
  19. 19. Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, 02115, MA, United States
  20. 20. Department of Health Sciences, The University of Chicago, Chicago, 60637, IL, United States
  21. 21. The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, 10029-6574, NY, United States
  22. 22. Department of Medical and Surgical Sciences, University of Bologna, Bologna, 40126, Italy

Source: Atmosphere Published:2019


Abstract

Household air pollution (HAP) is of public health concern, with ~3 billion people worldwide (including > 15 million in the US) exposed. HAP from coal use is a human lung carcinogen, yet the epidemiological evidence on carcinogenicity of HAP from biomass use, primarily wood, is not conclusive. To robustly assess biomass's carcinogenic potential, prospective studies of individuals experiencing a variety of HAP exposures are needed. We have built a global consortium of 13 prospective cohorts (HAPCO: Household Air Pollution Consortium) that have site- and disease-specific mortality and solid fuel use data, for a combined sample size of 587,257 participants and 57,483 deaths. HAPCO provides a novel opportunity to assess the association of HAP with lung cancer death while controlling for important confounders such as tobacco and outdoor air pollution exposures. HAPCO is also uniquely positioned to determine the risks associated with cancers other than lung as well as nonmalignant respiratory and cardiometabolic outcomes, for which prospective epidemiologic research is limited. HAPCO will facilitate research to address public health concerns associated with HAP-attributed exposures by enabling investigators to evaluate sex-specific and smoking status-specific effects under various exposure scenarios. © 2019 by the authors.