Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study

Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study Publisher Pubmed

Sheikh M^{1, 2} ; Poustchi H^{3, 4} ; Pourshams A^{1, 4} ; Khoshnia M^{1, 5} ; Gharavi A^{1, 5} ; Zahedi M⁶ ; Roshandel G^{1, 5} ; Sepanlou SG⁴ ; Fazel A⁷ ; Hashemian M^{1, 8} ; Abaei B⁴ ; Sotoudeh M^{1, 3, 4} ; Nikmanesh A^{1, 3, 4} ; Merat S^{3, 4} Show All Authors

Sheikh M^{1, 2}
Poustchi H^{3, 4}
Pourshams A^{1, 4}
Khoshnia M^{1, 5}
Gharavi A^{1, 5}
Zahedi M⁶
Roshandel G^{1, 5}
Sepanlou SG⁴
Fazel A⁷
Hashemian M^{1, 8}
Abaei B⁴
Sotoudeh M^{1, 3, 4}
Nikmanesh A^{1, 3, 4}
Merat S^{3, 4}
Etemadi A^{1, 8}
Moghaddam SN^{1, 4}
Islami F^{1, 9}
Kamangar F¹⁰
Pharoah PD¹¹
Dawsey SM⁸
Abnet CC⁸
Boffetta P¹²
Brennan P^{2, 13}
Malekzadeh R^{1, 3, 4, 14}

Show Affiliations

1. Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
2. Section of Genetics, International Agency for Research on Cancer, World Health Organization, Lyon, France
3. Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
4. Digestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
5. Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran
6. Ischemic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran
7. Cancer Research Center, Golestan University of Medical Sciences, Gorgan, Iran
8. Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States
9. Surveillance and Health Services Research, American Cancer Society, Atlanta, GA, United States
10. Department of Biology, School of Computer, Mathematical, and Natural Sciences, Morgan State University, Baltimore, MD, United States
11. Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
12. Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States
13. Genetic Epidemiology Group, Section of Genetics, International Agency for Research on Cancer, World Health Organization, 150 cours Albert Thomas, Lyon CEDEX 08, 69372, France
14. Digestive Diseases Research Institute, Tehran University of Medical Sciences, Shariati Hospital, Kargar-e-shomali Avenue, Tehran, 14117, Iran

Source: Environmental Health Perspectives Published:2020

Abstract

BACKGROUND: Three billion people burn nonclean fuels for household purposes. Limited evidence suggests a link between household fuel use and gastrointestinal (GI) cancers. OBJECTIVES: We investigated the relationship between indoor burning of biomass, kerosene, and natural gas with the subsequent risk of GI cancers. METHODS: During the period 2004–2008, a total of 50,045 Iranian individuals 40–75 years of age were recruited to this prospective population-based cohort. Upon enrollment, validated data were collected on demographics, lifestyle, and exposures, including detailed data on lifetime household use of different fuels and stoves. The participants were followed through August 2018 with <1% loss. RESULTS: During the follow-up, 962 participants developed GI cancers. In comparison with using predominantly gas in the recent 20-y period, using predominantly biomass was associated with higher risks of esophageal [hazard ratio (HR): 1.89; 95% confidence interval (CI): 1.02, 3.50], and gastric HR: 1.83; 95% CI: 1.01, 3.31) cancers, whereas using predominantly kerosene was associated with higher risk of esophageal cancer (HR: 1.84; 95% CI: 1.10, 3.10). Lifetime duration of biomass burning for both cooking and house heating (exclusive biomass usage) using heating-stoves without chimney was associated with higher risk of GI cancers combined (10-y HR: 1.14; 95% CI: 1.07, 1.21), esophageal (10-y HR: 1.19; 95% CI: 1.08, 1.30), gastric (10-y HR: 1.11; 95% CI: 1.00, 1.23), and colon (10-y HR: 1.26; 95% CI: 1.03, 1.54) cancers. The risks of GI cancers combined, esophageal cancer, and gastric cancer were lower when biomass was burned using chimney-equipped heating-stoves (strata difference p-values = 0:001, 0.003, and 0.094, respectively). Duration of exclusive kerosene burning using heating-stoves without chimney was associated with higher risk of GI cancers combined (10-y HR: 1.05; 95% CI: 1.00, 1.11), and esophageal cancer (10-y HR: 1.14; 95% CI: 1.04, 1.26). DISCUSSION: Household burning of biomass or kerosene, especially without a chimney, was associated with higher risk of some digestive cancers. Using chimney-equipped stoves and replacing these fuels with natural gas may be useful interventions to reduce the burden of GI cancers worldwide. © 2020, Public Health Services, US Dept of Health and Human Services. All rights reserved.

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Hossein Poustchi (83)

Reza Malekzadeh (79)

Style	Citing Format
MLA	Sheikh M, et al.. "Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study." Environmental Health Perspectives, vol. 128, no. 6, 2020, pp. 1-9.
APA	Sheikh M, Poustchi H, Pourshams A, Khoshnia M, Gharavi A, Zahedi M, Roshandel G, Sepanlou SG, Fazel A, Hashemian M, Abaei B, Sotoudeh M, Nikmanesh A, Merat S, Etemadi A, Moghaddam SN, Islami F, Kamangar F, Pharoah PD, ... Malekzadeh R (2020). Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study. Environmental Health Perspectives, 128(6), 1-9.
Chicago	Sheikh M, Poustchi H, Pourshams A, Khoshnia M, Gharavi A, Zahedi M, Roshandel G, et al.. "Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study." Environmental Health Perspectives 128, no. 6 (2020): 1-9.
Harvard	Sheikh M et al. (2020) 'Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study', Environmental Health Perspectives, 128(6), pp. 1-9.
Vancouver	Sheikh M, Poustchi H, Pourshams A, Khoshnia M, Gharavi A, Zahedi M, et al.. Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study. Environmental Health Perspectives. 2020;128(6):1-9.
BibTex	@article{ author = {Sheikh M and Poustchi H and Pourshams A and Khoshnia M and Gharavi A and Zahedi M and Roshandel G and Sepanlou SG and Fazel A and Hashemian M and Abaei B and Sotoudeh M and Nikmanesh A and Merat S and Etemadi A and Moghaddam SN and Islami F and Kamangar F and Pharoah PD and Dawsey SM and Abnet CC and Boffetta P and Brennan P and Malekzadeh R}, title = {Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study}, journal = {Environmental Health Perspectives}, volume = {128}, number = {6}, pages = {1-9}, year = {2020} }
RIS	TY - JOUR AU - Sheikh M AU - Poustchi H AU - Pourshams A AU - Khoshnia M AU - Gharavi A AU - Zahedi M AU - Roshandel G AU - Sepanlou SG AU - Fazel A AU - Hashemian M AU - Abaei B AU - Sotoudeh M AU - Nikmanesh A AU - Merat S AU - Etemadi A AU - Moghaddam SN AU - Islami F AU - Kamangar F AU - Pharoah PD AU - Dawsey SM AU - Abnet CC AU - Boffetta P AU - Brennan P AU - Malekzadeh R TI - Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study JO - Environmental Health Perspectives VL - 128 IS - 6 SP - 1 EP - 9 PY - 2020 ER -

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