Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Potential of Nanoparticles and Nanopolymers in Treatment of Age-Associated Diseases Publisher



Saadatpour F1 ; Mohammadipanah F1 ; Zohourian N1 ; Hodjat M2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Pharmaceutical Biotechnology Lab, Department of Microbiology, School of Biology, Center of Excellence in Phylogeny of Living Organisms, College of Science, University of Tehran, Tehran, 14155-6455, Iran
  2. 2. Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Advances in Natural Sciences: Nanoscience and Nanotechnology Published:2021


Abstract

Aging is an inevitable process caused by the accumulation of degenerative destructions, which ultimately leads to organism death. As the aging process occurs at the molecular, cellular, and tissue levels, understanding the whole details of age-related disorders is the prerequisite for the development of anti-aging therapy. More than 300 compounds of different sources have been reported with an anti-aging activity that controls age-related diseases through regulating single or multiple signalling pathways. Recent innovations in nanotechniques could lead to the development of nanomaterials having effects on age-associated malfunctions or acting as nanocarrier systems and distributers of anti-aging drugs. In this review, we summarised the molecular mechanisms of longevity and the prospect of developing anti-aging nanomaterials targeting aging pathways. © 2022 Vietnam Academy of Science & Technology.
Related Docs
View other Related Docs
1. Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4Th Edition)1, Autophagy (2021)
2. Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles, Autophagy (2019)
3. Aging and Cancer Prognosis, Cancer Immunology: Bench to Bedside Immunotherapy of Cancers# Second Edition (2020)
4. Opportunities and Challenges in Stem Cell Aging, Advances in Experimental Medicine and Biology (2021)
5. Autophagy Modulation in Breast Cancer Utilizing Nanomaterials and Nanoparticles, Frontiers in Oncology (2023)
6. Autophagy, Its Mechanisms and Regulation: Implications in Neurodegenerative Diseases, Ageing Research Reviews (2017)
7. Cellular Senescence and Ophthalmic Diseases: Narrative Review, Graefe's Archive for Clinical and Experimental Ophthalmology (2023)
8. Differential Effects of N-Tio2 Nanoparticle and Its Photo-Activated Form on Autophagy and Necroptosis in Human Melanoma A375 Cells, Journal of Cellular Physiology (2020)
Experts (# of related papers)
View all Related Experts
Mohammad Abdollahi (3)
Seyed Mojtaba Daghighi (2)
Other Related Docs
9. A Review on Liposome-Based Therapeutic Approaches Against Malignant Melanoma, International Journal of Pharmaceutics (2021)
10. Sildenafil Protective Effects on High Glucose-Induced Neurotoxicity in Pc12 Cells: The Role of Oxidative Stress, Apoptosis, and Inflammation Pathways in an in Vitro Cellular Model for Diabetic Neuropathy, Neurological Research (2018)
11. New Insights Into Designing Hybrid Nanoparticles for Lung Cancer: Diagnosis and Treatment, Journal of Controlled Release (2019)
12. Protein Corona Variation in Nanoparticles Revisited: A Dynamic Grouping Strategy, Colloids and Surfaces B: Biointerfaces (2019)
13. Palmitate-Induced Impairment of Autophagy Turnover Leads to Increased Apoptosis and Inflammation in Peripheral Blood Mononuclear Cells, Immunobiology (2018)
14. Clinical Applications of Nanomedicine in Cancer Therapy, Drug Discovery Today (2020)
15. Nexus Between in Silico and in Vivo Models to Enhance Clinical Translation of Nanomedicine, Nano Today (2021)
16. Cannabinoids As Anti-Ros in Aged Pancreatic Islet Cells, Life Sciences (2020)
17. Metal-Based Nanoparticles in Cancer Therapy: Exploring Photodynamic Therapy and Its Interplay With Regulated Cell Death Pathways, International Journal of Pharmaceutics (2024)
18. Manipulation of Molecular Pathways and Senescence Hallmarks by Natural Compounds in Fibroblast Cells, Journal of Cellular Biochemistry (2019)
19. Solid Silica Nanoparticles: Applications in Molecular Imaging, Contrast Media and Molecular Imaging (2015)
20. Novel Targeted Therapies for Rheumatoid Arthritis Based on Intracellular Signalling and Immunometabolic Changes: A Narrative Review, Frontiers in Bioscience - Landmark (2024)
21. Combining Nanotechnology and Gas Plasma As an Emerging Platform for Cancer Therapy: Mechanism and Therapeutic Implication, Oxidative Medicine and Cellular Longevity (2021)
22. Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Kidney, Journal of Controlled Release (2020)
23. Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook, Nanomedicine: Nanotechnology# Biology# and Medicine (2020)
24. Role of Autophagy in the Pathogenesis of Rheumatoid Arthritis: Latest Evidence and Therapeutic Approaches, Life Sciences (2020)
25. Age-Related Macular Degeneration and Neurodegenerative Disorders: Shared Pathways in Complex Interactions, Survey of Ophthalmology (2024)
26. Phosphodiesterase 4 and 7 Inhibitors Produce Protective Effects Against High Glucose-Induced Neurotoxicity in Pc12 Cells Via Modulation of the Oxidative Stress, Apoptosis and Inflammation Pathways, Metabolic Brain Disease (2018)
27. Green Synthesis of Silver Nanoparticles Using Trapa Natans Extract and Their Anticancer Activity Against A431 Human Skin Cancer Cells, Journal of Drug Delivery Science and Technology (2018)