Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook

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Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook Publisher Pubmed

Sepand MR¹ ; Ranjbar S² ; Kempson IM^{3, 4} ; Akbariani M¹ ; Muganda WCA⁵ ; Muller M⁵ ; Ghahremani MH¹ ; Raoufi M^{2, 5}

Source: Nanomedicine: Nanotechnology# Biology# and Medicine Published:2020

Abstract

Many tumors develop resistance to most of the apoptosis-based cancer therapies. In this sense targeting non-apoptotic forms of cell death including necroptosis, autophagy and ferroptosis may have therapeutic benefits in apoptosis-defective cancer cells. Nanomaterials have shown great advantages in cancer treatment owing to their unique characteristics. Besides, the capability of nanomaterials to induce different forms of cell death has gained widespread attention in cancer treatment. Reports in this field reflect the therapeutic potential of necroptotic cell death induced by nanomaterials in cancer. Also, autophagic cell death induced by nanomaterials alone and as a part of chemo-, radio- and photothermal therapy holds great promise as anticancer therapeutic option. Besides, ferroptosis induction by iron-based nanomaterials in drug delivery, immunotherapy, hyperthermia and imaging systems shows promising results in malignancies. Hence, this review is devoted to the latest efforts and the challenges in this field of research and its clinical merits. © 2020 Elsevier Inc.

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Style	Citing Format
MLA	Sepand MR, et al.. "Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook." Nanomedicine: Nanotechnology# Biology# and Medicine, vol. 29, no. , 2020, pp. -.
APA	Sepand MR, Ranjbar S, Kempson IM, Akbariani M, Muganda WCA, Muller M, Ghahremani MH, Raoufi M (2020). Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook. Nanomedicine: Nanotechnology# Biology# and Medicine, 29(), -.
Chicago	Sepand MR, Ranjbar S, Kempson IM, Akbariani M, Muganda WCA, Muller M, Ghahremani MH, Raoufi M. "Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook." Nanomedicine: Nanotechnology# Biology# and Medicine 29, no. (2020): -.
Harvard	Sepand MR et al. (2020) 'Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook', Nanomedicine: Nanotechnology# Biology# and Medicine, 29(), pp. -.
Vancouver	Sepand MR, Ranjbar S, Kempson IM, Akbariani M, Muganda WCA, Muller M, et al.. Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook. Nanomedicine: Nanotechnology# Biology# and Medicine. 2020;29():-.
BibTex	@article{ author = {Sepand MR and Ranjbar S and Kempson IM and Akbariani M and Muganda WCA and Muller M and Ghahremani MH and Raoufi M}, title = {Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook}, journal = {Nanomedicine: Nanotechnology# Biology# and Medicine}, volume = {29}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Sepand MR AU - Ranjbar S AU - Kempson IM AU - Akbariani M AU - Muganda WCA AU - Muller M AU - Ghahremani MH AU - Raoufi M TI - Targeting Non-Apoptotic Cell Death in Cancer Treatment by Nanomaterials: Recent Advances and Future Outlook JO - Nanomedicine: Nanotechnology# Biology# and Medicine VL - 29 IS - SP - EP - PY - 2020 ER -

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