Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles

Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles Publisher Pubmed

Mohammadinejad R¹ ; Moosavi MA² ; Tavakol S³ ; Vardar DO⁴ ; Hosseini A⁵ ; Rahmati M⁶ ; Dini L⁷ ; Hussain S⁸ ; Mandegary A⁹ ; Klionsky DJ¹⁰

Show Affiliations

1. Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
2. Department of Molecular Medicine, Institute of Medical Biotechnology, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran
3. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran
4. Sungurlu Vocational High School, Health Programs, Hitit University, Corum, Turkey
5. Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran
6. Cancer Biology Research Center, Tehran University of Medical Sciences, Tehran, Iran
7. CNR Nanotec, Lecce, Italy
8. Department of Physiology, Pharmacology and Neuroscience, West Virginia University, School of Medicine, Morgantown, WV, United States
9. Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
10. Life Sciences Institute, University of Michigan, Ann Arbor, MI, United States

Source: Autophagy Published:2019

Abstract

Nanomaterials have gained a rapid increase in use in a variety of applications that pertain to many aspects of human life. The majority of these innovations are centered on medical applications and a range of industrial and environmental uses ranging from electronics to environmental remediation. Despite the advantages of NPs, the knowledge of their toxicological behavior and their interactions with the cellular machinery that determines cell fate is extremely limited. This review is an attempt to summarize and increase our understanding of the mechanistic basis of nanomaterial interactions with the cellular machinery that governs cell fate and activity. We review the mechanisms of NP-induced necrosis, apoptosis and autophagy and potential implications of these pathways in nanomaterial-induced outcomes. Abbreviations: Ag, silver; CdTe, cadmium telluride; CNTs, carbon nanotubes; EC, endothelial cell; GFP, green fluorescent protein; GO, graphene oxide; GSH, glutathione; HUVECs, human umbilical vein endothelial cells; NP, nanoparticle; PEI, polyethylenimine; PVP, polyvinylpyrrolidone; QD, quantum dot; ROS, reactive oxygen species; SiO2, silicon dioxide; SPIONs, superparamagnetic iron oxide nanoparticles; SWCNT, single-walled carbon nanotubes; TiO2, titanium dioxide; USPION, ultra-small super paramagnetic iron oxide; ZnO, zinc oxide. © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group.

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Style	Citing Format
MLA	Mohammadinejad R, et al.. "Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles." Autophagy, vol. 15, no. 1, 2019, pp. 4-33.
APA	Mohammadinejad R, Moosavi MA, Tavakol S, Vardar DO, Hosseini A, Rahmati M, Dini L, Hussain S, Mandegary A, Klionsky DJ (2019). Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles. Autophagy, 15(1), 4-33.
Chicago	Mohammadinejad R, Moosavi MA, Tavakol S, Vardar DO, Hosseini A, Rahmati M, Dini L, Hussain S, Mandegary A, Klionsky DJ. "Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles." Autophagy 15, no. 1 (2019): 4-33.
Harvard	Mohammadinejad R et al. (2019) 'Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles', Autophagy, 15(1), pp. 4-33.
Vancouver	Mohammadinejad R, Moosavi MA, Tavakol S, Vardar DO, Hosseini A, Rahmati M, et al.. Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles. Autophagy. 2019;15(1):4-33.
BibTex	@article{ author = {Mohammadinejad R and Moosavi MA and Tavakol S and Vardar DO and Hosseini A and Rahmati M and Dini L and Hussain S and Mandegary A and Klionsky DJ}, title = {Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles}, journal = {Autophagy}, volume = {15}, number = {1}, pages = {4-33}, year = {2019} }
RIS	TY - JOUR AU - Mohammadinejad R AU - Moosavi MA AU - Tavakol S AU - Vardar DO AU - Hosseini A AU - Rahmati M AU - Dini L AU - Hussain S AU - Mandegary A AU - Klionsky DJ TI - Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles JO - Autophagy VL - 15 IS - 1 SP - 4 EP - 33 PY - 2019 ER -

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