The Prevalence of Hepatitis C and Hepatitis B in Lesbian, Gay, Bisexual and Transgender Populations: A Systematic Review and Meta-Analysis Publisher Pubmed



Moradi G¹ ; Soheili M² ; Rashti R¹ ; Dehghanbanadaki H³ ; Nouri E¹ ; Zakaryaei F⁴ ; Amini EE¹ ; Baiezeedi S⁵ ; Ahmadi S¹ ; Moradi Y^{1, 6} Show Affiliations
Source: European Journal of Medical Research Published:2022

Abstract

Objectives: This study aimed to systematically review the literature on the prevalence of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections in transgender and LGBT people and determine their pooled estimates worldwide. Methods: Databases (PubMed, Scopus, Web of Science, Embase, Ovid, Cochrane, PsycInfo) were searched from April 2000 to July 2021. The analyses were executed using the random-effects model in Stata 16. Results: Ten studies, including eight studies on four transgender people and two studies on 2150 LGBTs, were included. The pooled prevalence of HCV and HBV in all transgender populations globally were 9% (95% CI 3–15%) and 11% (95% CI 2–20%), respectively. The corresponding prevalence in male-to-female transgender people were estimated as 5% (95% CI 1–9%) and 6% (95% CI 3–10%), respectively. These estimates in American transgenders were 10% (95% CI 5–25%) and 16% (95% CI 8–23%), respectively. Conclusion: This study was identified the overall prevalence of HBV and HCV infections in transgender people, which were higher than those in the general population. © 2022, The Author(s).