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Severe Acute Respiratory Syndrome and Thyroid: A Molecular Point of View Publisher Pubmed



Sadoughi F1 ; Maleki Dana P1 ; Hallajzadeh J2 ; Asemi Z1 ; Mansournia MA3 ; Yousefi B4, 5
Authors

Source: Clinical Nutrition ESPEN Published:2022


Abstract

SARS-CoV-2 and some other members of Coronaviridae family have recently forced a great deal of health, social, and economic issues globally. To that end, investigations have been oriented towards finding ways for reducing the burden of COVID-19. One of the occurrences which stands in the way of making the treatment of this disease less complicated is the way coronaviruses involve a variety of cells, tissues, organs, and even systems. This action is possible as a result of viral attachment to the angiotensin-converting enzyme 2 or ACE2. Thus, any kind of cell expressing ACE2 is prone to be affected by both SARS-COV and SARS-COV-2. Endocrine system is one of these at-risk systems. In this review, we have considered the relation between coronaviruses and one of the most essential organs of endocrine system: thyroid gland. This relation can be probed from two aspects: how underlying thyroid dysfunction can increase the risk of being infected by these viruses and how these viruses can alter the function of thyroid gland. © 2022 European Society for Clinical Nutrition and Metabolism
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