Does Dietary Intake of Caffeine Have an Effect on Transient Global Amnesia? Publisher Pubmed



Zeinalabedini M¹ ; Mousavi Z² ; Amjadi A³ ; Shapouri M⁴ ; Aminnezhadkavkani B⁵ ; Masoumvand M⁶ ; Mobarakeh KA⁷ ; Gholamalizadeh M⁸ ; Valisoltani N⁹ ; Mohammadi S¹⁰ ; Khoshdooz S¹¹ ; Doaei S¹² ; Kooshki A¹³
Source: Neuropsychopharmacology Reports Published:2024

Abstract

Aim: Amnesia is a cognitive disorder that may lead to memory loss. Caffeine is a psychoactive substance which have an effect on memory and cognitive functions. This study aimed to assess the association of transient global amnesia (TGA) with dietary intake of caffeine. Methods: This cross-sectional study was conducted on the Sabzevar Persian cohort data of 258 patients with TGA and 520 healthy individuals in Sabzevar, Iran. The Nutritional data were gathered in face-to-face interviews using a valid Food Frequency Questionnaire. Different models of logistic regression were used to determine the association between TGA and dietary caffeine intake after adjusting the confounders including age, sex, education, job, marital status, physical activity, BMI, and calorie intake. Results: There was no significant difference in terms of dietary calorie intake of (2279.5 ± 757.9 vs. 2365.5 ± 799.5, p = 0.19), protein (70.79 ± 25.27 vs. 72.94 ± 24.83, p = 0.31), fat (59.97 ± 23.79 vs. 60.13 ± 26.38, p = 0.93), carbohydrate (376 ± 134 vs. 393.1 ± 137.8, p = 0.14), and caffeine (196.4 ± 127.9 vs. 186.3 ± 128.5, p = 0.36) between the groups. No significant association was found between TGA and dietary intake of caffeine (OR: 0.99, 95% CI: 0.99–1.01, p = 0.36). The results did not change after adjusting the confounders. Conclusions: No significant association was found between TGA and dietary intake of caffeine. Further prospective studies are required to confirm this finding. © 2023 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Neuropsychopharmacology.