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Templated Roughness on the Surface of Polyamide Nanofibrous Mat by Mesh Electrospinning Publisher



Saadatmand MM1 ; Yazdanshenas ME1 ; Khajavi R2 ; Mighani F3 ; Toliyat T4
Authors
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Authors Affiliations
  1. 1. Department of Textile and Polymer Engineering, Yazd Branch, Islamic Azad University, Yazd, Iran
  2. 2. Department of Polymer and Textile Engineering, South Tehran Branch, Islamic Azad University, Tehran, Iran
  3. 3. Scientific Member of Weed Research Department, Iranian Plant Protection Research Institute, Tehran, Iran
  4. 4. Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Oriental Journal of Chemistry Published:2017


Abstract

In this study, it was aimed to present a nanofibrous scaffold with intentional roughness through a new electrospinning method called “mesh electrospinning method”. Firstly, polyamide nylon 6 granules were dissolved in formic acid in different concentration (10-35 %w/v). A mesh template was placed between tip and collector in different distance (4 positions) in a conventional electrospinning line. The number of mesh layers and effects of processing parameters also considered. As it was expected, the results show that, increasing the polymer solution lead to increase fiber diameter, from 84 nm for 20% to 265 nm for 30%. The results showed that the layer just formed when the mesh was placed just on the collector. On the other hand, with increasing the number of mesh layers (1&3), roughness decreased (55-60%). It was also observed that the produced roughness is governed by the geometry of the mesh. To consider the ability for controlling the roughness, the produced roughness can be applied for drug delivery purposes transdermal drug delivery. © 2017, Oriental Scientific Publishing Company. All rights reserved.