Immunodeficiencies Publisher



Sadeghalvad M^{1, 2, 3} ; Rezaei N^{1, 2, 3}
Source: Clinical Immunology Published:2022

Abstract

Immunodeficiency refers to a group of diseases in which defects in one or more molecules or cells associated with the immune system lead to defects in the development of immune responses to pathogens. Immunodeficiency includes any developmental, differentiation, or functional defect of one or more groups of immune system components and is divided into primary immunodeficiencies (inborn errors of immunity) and secondary immunodeficiencies (acquired immunodeficiencies). Early diagnosis of immunodeficiency disorders, particularly in childhood, can be very beneficial in treating, decreasing symptoms, and reducing mortality in children. Understanding deficiency disorders, symptoms, and approaches for diagnosing them can thus be a helpful step toward the early detection of these diseases. In this chapter, we sought to present the types of immunodeficiency diseases, their possible diagnosis and treatment. © 2023 Elsevier Inc. All rights reserved.