Potentially Effective Natural Drugs in Treatment for the Most Common Rheumatic Disorder: Osteoarthritis

Potentially Effective Natural Drugs in Treatment for the Most Common Rheumatic Disorder: Osteoarthritis Publisher Pubmed

Farzaei MH^{1, 2} ; Farzaei F³ ; Gooshe M⁵ ; Abbasabadi Z² ; Rezaei N^{6, 7, 8, 9} ; Abdolghaffari AH^{10, 11}

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1. Department of Traditional Pharmacy, Tehran University of Medical Sciences, Tehran, 1417653761, Iran
2. Kermanshah University of Medical Sciences, Kermanshah, 6734667149, Iran
3. College of Veterinary Medicine, Kermanshah Razi University, Kermanshah, 6715685414, Iran
4. Tehran University of Medical Sciences, Tehran, 1417614411, Iran
5. Studentsâ€™ Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, 1417614411, Iran
6. Research Center for Immunodeficiencies, Childrenâ€™s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
7. Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran
8. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
9. Department of Infection and Immunity, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
10. Pharmacology and Applied Medicine Department of Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj-Qazvin Freeway, Supa, Boulevard, Jahade-Daneshgahi Research Society, P.O Box: 141554364, Karaj, Alborz, Iran
11. International Campus, Tehran University of Medical Sciences (ICTUMS), Tehran, 1417653861, Iran

Source: Rheumatology International Published:2015

Abstract

Osteoarthritis (OA) is a chronic condition in which imbalance between anabolic and catabolic mediators occurs leading to the destruction of homeostasis of articular cartilage. The current drugs in the management of OA can just alleviate symptoms. Hence, the research tendency toward exploration of novel sources has been grown up in order to achieve safe and efficacious drugs. Meanwhile, various components exist as novel natural drugs that may possess favorable properties for the management of OA. This review focuses on the most efficacious medicinal plants and their phytochemical agents, which have been consumed for the management of OA. Moreover, evaluation of their efficacy and molecular mechanisms of action are discussed based on numerous modern experimental investigations. More research is needed to develop therapeutic agents with disease-modifying properties to treat OA. © 2014, Springer-Verlag Berlin Heidelberg.

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Style	Citing Format
MLA	Farzaei MH, et al.. "Potentially Effective Natural Drugs in Treatment for the Most Common Rheumatic Disorder: Osteoarthritis." Rheumatology International, vol. 35, no. 5, 2015, pp. 799-814.
APA	Farzaei MH, Farzaei F, Gooshe M, Abbasabadi Z, Rezaei N, Abdolghaffari AH (2015). Potentially Effective Natural Drugs in Treatment for the Most Common Rheumatic Disorder: Osteoarthritis. Rheumatology International, 35(5), 799-814.
Chicago	Farzaei MH, Farzaei F, Gooshe M, Abbasabadi Z, Rezaei N, Abdolghaffari AH. "Potentially Effective Natural Drugs in Treatment for the Most Common Rheumatic Disorder: Osteoarthritis." Rheumatology International 35, no. 5 (2015): 799-814.
Harvard	Farzaei MH et al. (2015) 'Potentially Effective Natural Drugs in Treatment for the Most Common Rheumatic Disorder: Osteoarthritis', Rheumatology International, 35(5), pp. 799-814.
Vancouver	Farzaei MH, Farzaei F, Gooshe M, Abbasabadi Z, Rezaei N, Abdolghaffari AH. Potentially Effective Natural Drugs in Treatment for the Most Common Rheumatic Disorder: Osteoarthritis. Rheumatology International. 2015;35(5):799-814.
BibTex	@article{ author = {Farzaei MH and Farzaei F and Gooshe M and Abbasabadi Z and Rezaei N and Abdolghaffari AH}, title = {Potentially Effective Natural Drugs in Treatment for the Most Common Rheumatic Disorder: Osteoarthritis}, journal = {Rheumatology International}, volume = {35}, number = {5}, pages = {799-814}, year = {2015} }
RIS	TY - JOUR AU - Farzaei MH AU - Farzaei F AU - Gooshe M AU - Abbasabadi Z AU - Rezaei N AU - Abdolghaffari AH TI - Potentially Effective Natural Drugs in Treatment for the Most Common Rheumatic Disorder: Osteoarthritis JO - Rheumatology International VL - 35 IS - 5 SP - 799 EP - 814 PY - 2015 ER -

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