Efficacy, Uses, and Limitations of Photobiomodulation on Damaged Nerves Regeneration in Dentistry



Fekrazad R^{1, 2} ; Hakimiha N³ ; Moslemi N⁴ Show Affiliations
Source: Laser Light Therapy in Dentistry: Efficacy# Uses and Limitations Published:2021

Abstract

Peripheral nerve injuries associated with oral and maxillofacial surgeries and trauma result in unpleasant outcome for patients. Thus, in this chapter, efficacy and clinical applications of photobiomodulation therapy (PBMT) on recovery of the injured nerves are investigated. According to results of the related reviewed studies, PBMT as a noninvasive approach is able to exert beneficial effects on promotion and acceleration of nerve recovery, including enhancement of neurosensory and functional recovery. Selection of proper wavelength and dosimetry parameters is of paramount importance in achieving effective results with PBMT. Hence, the future studies are suggested to assess the effects of multi-wavelength PBMT, to compare modes of pulse and continuous laser irradiation, or to evaluate the effects of PBMT on nerve injuries with different time intervals passed from occurrence of injury. In addition, different doses of PBMT in early and late phases of nerve regeneration can be considered as topics of further research. Multiple-session treatment procedure nature of PBMT that causes the repeated reference of patients to clinic and misdiagnosis of nerve injury are other limitations of this procedure. Accordingly, further well-designed studies are required to increase level of evidence and to achieve a standardized and safe protocol for the patients. © 2021 Nova Science Publishers, Inc.