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Death Due to Covid-19 in an Infant With Combined Immunodeficiencies Publisher Pubmed



Ahanchian H1 ; Moazzen N1 ; Saeidinia A2 ; Joghatayi SH2 ; Khoshkhui M1 ; Aelami MH3 ; Haghi NSM1 ; Rezaei N4, 5, 6
Authors
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Authors Affiliations
  1. 1. Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  3. 3. Department of Pediatrics and Hand Hygiene and Infection Control Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
  4. 4. Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Endocrine# Metabolic and Immune Disorders - Drug Targets Published:2021


Abstract

Background: Severe Acute Respiratory Syndrome Coronavirus 2 has affected millions of people, and especially in adult patients with underlying diseases lead to death. Meanwhile pediatric patients with inherited defects of T cell should be prone to viral diseases. Case Presentation: Herein, we report an infant with severe combined immunodeficiencies, who were affected and died because of COVID-19. Conclusion: Considering the importance of finding how immune system can affect the viral infection, presentation of COVID-19 in immune deficient patients can be valuable. © 2021 Bentham Science Publishers.
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