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Introduction on Stem Cell Therapy and Regeneration Publisher



Masrour M1 ; Moeinafshar A1 ; Rezaei N2, 3, 4
Authors
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Authors Affiliations
  1. 1. School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  2. 2. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  3. 3. Department of Immunology, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  4. 4. Network of Immunity in Infection, Malignancy, and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Comprehensive Hematology and Stem Cell Research: Volume 1-5 Published:2024


Abstract

Stem cells are cellular subsets with developmental and regenerative functions with a wide range of differentiation potency, ranging from totipotent stem cells capable of differentiating into extra- and intra-embryonal lineages to unipotent stem cells with variable sources of retrieval. In contrast to the early developmental stages, adult tissues possess a limited regenerative potential, negatively affecting the rehabilitation and recovery of patients. The therapeutic application of stem cells in regenerative medicine is an area of great potential and has been investigated in a variety of pre-clinical and clinical studies, ever since the first reports of stem cell administration in the 1950s. In this article, an introduction to stem cell therapy and the administration of stem cell subsets in regenerative medicine in pathological conditions has been discussed. © 2024 Elsevier Inc. All rights are reserved.
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