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Molecular Recognition Ability of Molecularly Imprinted Polymer Nano- and Micro-Particles by Reversible Addition-Fragmentation Chain Transfer Polymerization Publisher



Abdollahi E1 ; Abdouss M1 ; Salamikalajahi M2 ; Mohammadi A3, 4
Authors
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Authors Affiliations
  1. 1. Department of Chemistry, Amirkabir University of Technology, Tehran, Iran
  2. 2. Department of Polymer Engineering, Sahand University of Technology, Tabriz, Iran
  3. 3. Faculty of Pharmacy, Department of Drug and Food Control, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Nanotechnology Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Polymer Reviews Published:2016


Abstract

The role of molecularly imprinted polymers (MIPs) is changing from academic to applied researches. Challenging problems about MIP will be more highlighted in applicable uses and solving these problems is vital. The controlled/“living” radical polymerization (CLRP) techniques are applicable to solve the challenging problems in MIPs. The “living” nature of CLRP helps to improve the heterogeneity of binding sites in MIPs as a main challenge where precise control over sizes, compositions, and surface functionalities is achieved. Among different techniques of CLRP, reversible addition-fragmentation chain transfer (RAFT) technique presents distinguished benefits such as compatibility and tolerance to a wide range of functional monomers and mild reaction conditions rather than other CLRP techniques. In this review, in order to obtain more insights into the potential benefits of RAFT polymerization in fabrication of nano and micro MIP networks, recent research in advanced MIP materials for different templates with improved morphology, efficiency, and binding capacities with respect to traditional free radical polymerization (FRP) will be discussed. MIPs prepared via RAFT method have advantages of MIPs as high performance molecular recognition devices and CLRP as controllable polymerization mechanism, simultaneously. © 2016 Taylor & Francis Group, LLC.