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Advances in Cryopreservation of Spermatogonial Stem Cells and Restoration of Male Fertility Publisher Pubmed



Aliakbari F1 ; Yazdekhasti H1 ; Abbasi M1 ; Hajian Monfared M1 ; Baazm M2
Authors
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Authors Affiliations
  1. 1. Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Anatomy, School of Medicine, Arak University of Medical Sciences, Arak, Iran

Source: Microscopy Research and Technique Published:2016


Abstract

Spermatogenesis is a highly complicated process which initiated by spermatogonial stem cells (SSCs). SSCs are the only cell type that can restore fertility in infertile recipient after SSCs transplantation. SSCs damage during cancer diagnosis and therapy and their depletion may be cause of male infertility in cancer survivors. In this review, used experimental methods regarding SSCs and testis tissue cryopreservation have been reviewed with a special focus on animal models and human which have generated the majority of data about SSCs and the cryopreservation process. © 2016 Wiley Periodicals, Inc.
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