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Animal- and Human-Based Evidence for the Protective Effects of Stem Cell Therapy Against Cardiovascular Disorders Publisher Pubmed



Pooria A1 ; Pourya A2 ; Gheini A1
Authors
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Authors Affiliations
  1. 1. Department of Cardiology, Lorestan University of Medical Sciences, Khoramabad, Iran
  2. 2. Student of Research committee, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Cellular Physiology Published:2019


Abstract

The increasing rate of mortality and morbidity because of cardiac diseases has called for efficient therapeutic needs. With the advancement in cell-based therapies, stem cells are abundantly studied in this area. Nearly, all sources of stem cells are experimented to treat cardiac injuries. Tissue engineering has also backed this technique by providing an advantageous platform to improve stem cell therapy. After in vitro studies, primary treatment-based research studies comprise small and large animal studies. Furthermore, these studies are implemented in human models in the form of clinical trials. Purpose of this review is to highlight the animal- and human-based studies, exploiting various stem cell sources, to treat cardiovascular disorders. © 2019 Wiley Periodicals, Inc.
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