Cytotoxic Abietane Diterpenoids From Salvia Leriifolia Benth

Cytotoxic Abietane Diterpenoids From Salvia Leriifolia Benth Publisher Pubmed

Sarhadi E¹ ; Nejad Ebrahimi S² ; Hadjiakhoondi A^{1, 3} ; Abbasmohammadi M⁴ ; Manayi A¹ ; Parisi V⁵ ; Pessolano E⁵ ; Petrella A⁵ ; De Tommasi N⁵

Show Affiliations

1. Medicinal Plants Research Centr, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran
3. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran
5. Dipartimento di Farmacia, Universita Degli Studi di Salerno, Via Giovanni Paolo II NÂ° 132, Fisciano, 84084, SA, Italy

Source: Phytochemistry Published:2022

Abstract

The Phytochemical profiling of the root extract of Salvia leriifolia, an endemic plant of Iran, was investigated and 16 abietane diterpenes were isolated, and three were original compounds. 1D and 2D NMR and HRMS performed structural elucidation. The absolute configuration of the previously unreported compounds was determined by circular dichroism (ECD). The cytotoxicity of the isolated compounds was investigated against AGS, MIA PaCa-2, HeLa, and MCF-7 cell lines by the MTT assay. The known diterpene pisiferal possesses high cytotoxicity against all investigated cell lines at a concentration between 9.3 ± 0.6 and 14.38 ± 1.4 μM. © 2022 Elsevier Ltd

Related Docs

1. A New Rearranged Tricyclic Abietane Diterpenoid From Salvia Chloroleuca Rech. F. & Allen, Natural Product Research (2016)

2. New Diterpenoids From the Aerial Parts of Salvia Reuterana, Iranian Journal of Pharmaceutical Research (2019)

3. Chemical Composition and Antioxidant Activity of Root Essential Oil of Different Salvia Leriifolia Populations, Journal of Essential Oil-Bearing Plants (2021)

4. Antiprotozoal Activity of Diterpenoids Isolated From Zhumeria Majdae- Absolute Configuration by Circular Dichroism, DARU# Journal of Pharmaceutical Sciences (2020)

5. Composition and Antibacterial Activity of Essential Oils From Aerial Parts of Salvia Lerrifolia Populations From Iran, Journal of Essential Oil-Bearing Plants (2020)

6. Cytotoxic Activity of Abietane Diterpenoids From Roots of Salvia Sahendica by Hplc-Based Activity Profiling, Revista Brasileira de Farmacognosia (2018)

Experts (# of related papers)

View all Related Experts

Abbas Hadjiakhoondi (3)

Azadeh Manayi (2)

Style	Citing Format
MLA	Sarhadi E, et al.. "Cytotoxic Abietane Diterpenoids From Salvia Leriifolia Benth." Phytochemistry, vol. 202, no. , 2022, pp. -.
APA	Sarhadi E, Nejad Ebrahimi S, Hadjiakhoondi A, Abbasmohammadi M, Manayi A, Parisi V, Pessolano E, Petrella A, De Tommasi N (2022). Cytotoxic Abietane Diterpenoids From Salvia Leriifolia Benth. Phytochemistry, 202(), -.
Chicago	Sarhadi E, Nejad Ebrahimi S, Hadjiakhoondi A, Abbasmohammadi M, Manayi A, Parisi V, Pessolano E, Petrella A, De Tommasi N. "Cytotoxic Abietane Diterpenoids From Salvia Leriifolia Benth." Phytochemistry 202, no. (2022): -.
Harvard	Sarhadi E et al. (2022) 'Cytotoxic Abietane Diterpenoids From Salvia Leriifolia Benth', Phytochemistry, 202(), pp. -.
Vancouver	Sarhadi E, Nejad Ebrahimi S, Hadjiakhoondi A, Abbasmohammadi M, Manayi A, Parisi V, et al.. Cytotoxic Abietane Diterpenoids From Salvia Leriifolia Benth. Phytochemistry. 2022;202():-.
BibTex	@article{ author = {Sarhadi E and Nejad Ebrahimi S and Hadjiakhoondi A and Abbasmohammadi M and Manayi A and Parisi V and Pessolano E and Petrella A and De Tommasi N}, title = {Cytotoxic Abietane Diterpenoids From Salvia Leriifolia Benth}, journal = {Phytochemistry}, volume = {202}, number = {}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Sarhadi E AU - Nejad Ebrahimi S AU - Hadjiakhoondi A AU - Abbasmohammadi M AU - Manayi A AU - Parisi V AU - Pessolano E AU - Petrella A AU - De Tommasi N TI - Cytotoxic Abietane Diterpenoids From Salvia Leriifolia Benth JO - Phytochemistry VL - 202 IS - SP - EP - PY - 2022 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract