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Anticoagulation in the Management of Septic Cavernous Sinus Thrombosis Secondary to Rhino-Orbito-Cerebral Mucormycosis: A Retrospective Real-World Experience Publisher



Amani K1 ; Shahbazi M2 ; Behkar A3 ; Farahmand G1 ; Ghafouri S1 ; Heydari S1 ; Kaeedi M1 ; Magrouni H1 ; Alizadeh F1 ; Ghabaee M2 ; Sarraf P2 ; Tafakhori A2 ; Amirifard H2 ; Ranjiburachaloo S2 Show All Authors
Authors
  1. Amani K1
  2. Shahbazi M2
  3. Behkar A3
  4. Farahmand G1
  5. Ghafouri S1
  6. Heydari S1
  7. Kaeedi M1
  8. Magrouni H1
  9. Alizadeh F1
  10. Ghabaee M2
  11. Sarraf P2
  12. Tafakhori A2
  13. Amirifard H2
  14. Ranjiburachaloo S2
  15. Mohammadianinejad SE2
  16. Jameie M2
  17. Harirchian MH2
Show Affiliations
Authors Affiliations
  1. 1. Neurology Ward, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Iranian Center of Neurological Research, Neuroscience Institute, Imam Khomeini Hospital Complex Tehran University of Medical Sciences, Tehran, Iran
  3. 3. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Current Journal of Neurology Published:2024


Abstract

Background: COVID-19 was associated with an increased number of patients with mucormycosis (MCR), followed by septic cavernous sinus thrombosis (SCST). We evaluated the association between anticoagulation (AC) and mortality/morbidity of COVID-19-associated MCR (CAM)-induced SCST. Methods: In this retrospective study, neurological sequelae, functional outcomes, and in-hospital mortality were compared between AC receivers and non-receivers. In addition, the association between AC and survivability was examined. Results: Twenty-nine patients (17 male; mean age: 51.27 years) with CAM-induced SCST were included in the study. The median intervals between COVID-19 and MCR, and COVID-19 and SCST were 19 and 27 days, respectively. © 2024 Iranian Neurological Association, and Tehran University of Medical Sciences.
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