Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Breast Cancer Incidence Trends in Golestan, Iran: An Age-Period-Cohort Analysis by Ethnic Region, 2004-2018 Publisher Pubmed



Ghasemikebria F1 ; Fazel A2 ; Semnani S1 ; Etemadi A3 ; Naeimitabiei M2 ; Hasanpourheidari S1 ; Salamat F1 ; Jafaridelouie N1 ; Sedaghat S4 ; Sadeghzadeh H4 ; Akbari M5 ; Mehrjerdian M6 ; Weiderpass E7 ; Roshandel G1 Show All Authors
Authors
  1. Ghasemikebria F1
  2. Fazel A2
  3. Semnani S1
  4. Etemadi A3
  5. Naeimitabiei M2
  6. Hasanpourheidari S1
  7. Salamat F1
  8. Jafaridelouie N1
  9. Sedaghat S4
  10. Sadeghzadeh H4
  11. Akbari M5
  12. Mehrjerdian M6
  13. Weiderpass E7
  14. Roshandel G1
  15. Bray F8
  16. Malekzadeh R9
Show Affiliations
Authors Affiliations
  1. 1. Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran
  2. 2. Cancer Research Center, Golestan University of Medical Sciences, Gorgan, Iran
  3. 3. Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States
  4. 4. Deputy of Public Health, Golestan University of Medical Sciences, Gorgan, Iran
  5. 5. Deputy of Treatment, Golestan University of Medical Sciences, Gorgan, Iran
  6. 6. Department of Pathology, Golestan University of Medical Sciences, Gorgan, Iran
  7. 7. Office of the Director, International Agency for Research on Cancer (IARC), Lyon, France
  8. 8. Cancer Surveillance Branch, International Agency for Research on Cancer (IARC), World Health Organization (WHO), Lyon, France
  9. 9. Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Cancer Epidemiology Published:2024


Abstract

Background: We aimed to examine the effects of age, diagnosis year (calendar period) and birth year (cohort) on the incidence trends of breast cancer among Golestan women, Northeast Iran, 2004–2018. Methods: Incidence data were obtained by residential status (urban/rural) and ethnic region (Turkmens/non-Turkmens). We calculated age-standardized incidence rates (ASRs) per 100,000 person-years. The estimated annual percentage change (EAPC) were calculated, and age-period-cohort (APC) models fitted to assess non-linear effects of period and cohort as incidence rate ratios (IRRs). Results: The total number of female breast cancer cases in Golestan, 2004–2018, were 3853, with an overall ASR of 31.3. We found higher rates in urban population (40.5) and non-Turkmens region (38.5) compared to rural area (20.8) and Turkmens region (20.2), respectively. There were increasing trends in incidence rates overall (EAPC= 4.4; 95%CI: 2.2, 6.7), with greater changes in rural areas (EAPC=5.1), particularly among non-Turkmens (EAPC=5.8). The results of the APC analysis indicate the presence of significant non-linear cohort effects with increasing IRRs across successive birth cohorts (IRR=0.1 and IRR= 2.6 for the oldest and the youngest birth cohorts vs. the reference birth cohort, respectively). Conclusion: We found increasing trends in breast cancer incidence among Golestan women over the study period, with disparities in patterns and trends by residence area and ethnic region. The observed cohort effects suggest an increasing prevalence of key risk factors for breast cancer in this Iranian population. Further investigations are warranted to clarify the relationships between determinants such as reproductive factors and ethnicity in the region. © 2024 Elsevier Ltd
Related Docs
View other Related Docs
1. Colorectal Cancer Incidence Trends in Golestan, Iran: An Age-Period-Cohort Analysis 2004–2018, Cancer Epidemiology (2023)
2. Esophageal and Gastric Cancer Incidence Trends in Golestan, Iran: An Age-Period-Cohort Analysis 2004 to 2018, International Journal of Cancer (2023)
3. Examining the Completeness of Breast Cancer Pathology Reports Registered in the Population-Based Cancer Registration System and Spatial Analysis of the Incidence of This Cancer in Iran in 2016, International Journal of Cancer Management (2023)
4. Building a Cancer Biobank in a Low-Resource Setting in Northern Iran: The Golestan Cancer Biobank, Archives of Iranian Medicine (2021)
5. Cancer in Iran 2008 to 2025: Recent Incidence Trends and Short-Term Predictions of the Future Burden, International Journal of Cancer (2021)
6. Cancer Incidence in Iran in 2014: Results of the Iranian National Population-Based Cancer Registry, Cancer Epidemiology (2019)
7. Building Cancer Registries in a Lower Resource Setting: The 10-Year Experience of Golestan, Northern Iran, Cancer Epidemiology (2018)
8. Current Status and Future Prospects for Esophageal Cancer, Cancers (2023)
Experts (# of related papers)
View all Related Experts
Reza Malekzadeh (21)
Kazem Zendehdel (13)
Other Related Docs
9. Recent Cancer Incidence Trends and Short-Term Predictions in Golestan, Iran 2004–2025, Cancer Epidemiology (2020)
10. Trends in the Incidence of Stomach Cancer in Golestan Province, a High-Risk Area in Northern Iran, 2004-2016, Archives of Iranian Medicine (2020)
11. Epidemiology of Head and Neck Cancers in Northern Iran: A 10-Year Trend Study From Golestan Province, Archives of Iranian Medicine (2018)
12. A Single Nucleotide Polymorphism in the Aldh2 Gene Modifies the Risk of Esophageal Squamous Cell Carcinoma in Brca2 P.K3326∗ Carriers, PLoS ONE (2023)
13. The 15-Year National Trends of Endocrine Cancers Incidence Among Iranian Men and Women; 2005–2020, Scientific Reports (2023)
14. Clinical Breast Cancer Registry of Ir. Iran (Cbcr-Ir): Study Protocol and First Results, Archives of Iranian Medicine (2023)
15. Prevalence of Metabolic Syndrome in Iran: A 2011 Update, Journal of Diabetes (2017)
16. Completeness and Accuracy of Death Registry Data in Golestan, Iran, Archives of Iranian Medicine (2019)
17. National and Subnational Burden of Female and Male Breast Cancer and Risk Factors in Iran From 1990 to 2019: Results From the Global Burden of Disease Study 2019, Breast Cancer Research (2023)
18. Dietary Choline and Betaine Intake and Risk of Colorectal Cancer in an Iranian Population, Cancers (2023)
19. Incidence and Mortality of Various Cancers in Iran and Compare to Other Countries: A Review Article, Iranian Journal of Public Health (2018)
20. Determination of a Cost-Effectiveness Threshold for Cancer Interventions in Iran, Frontiers in Oncology (2022)
21. Dietary Ruminant and Industrial Trans-Fatty Acids Intake and Colorectal Cancer Risk, Nutrients (2022)
22. Physical Activity, Sedentary Behavior and Correlates Among Students of Tehran University of Medical Sciences, Acta Medica Iranica (2019)
23. Geographical and Socioeconomic Inequalities in Female Breast Cancer Incidence and Mortality in Iran: A Bayesian Spatial Analysis of Registry Data, PLoS ONE (2021)
24. Colorectal Cancer: Epidemiology, Risk Factors, and Prevention, Cancers (2024)
25. Pattern and Determinant Factors of Birth Intervals Among Iranian Women: A Semi-Parametric Multilevel Survival Model, Journal of Biosocial Science (2020)
26. Evaluation of Factors Related to Short-Term and Long-Term Survival of Breast Cancer Patients by Mixture Cure Model, Iranian Journal of Breast Diseases (2022)
27. Estimates of Incidence, Prevalence, Mortality, and Disability-Adjusted Life Years of Lung Cancer in Iran, 1990–2019: A Systematic Analysis From the Global Burden of Disease Study 2019, Cancer Medicine (2022)
28. The Relationship Between Religious Well-Being, Existential Well-Being, Fear of Progression and Quality of Life in Patients With Cancer: The Mediating Role of Hope, Asian Pacific Journal of Cancer Prevention (2024)
29. Association Between Dietary Fat Intake and Colorectal Cancer: A Multicenter Case-Control Study in Iran, Frontiers in Nutrition (2022)
30. Diseases and Health Outcomes Registry Systems in I.R. Iran: Successful Initiative to Improve Public Health Programs, Quality of Care, and Biomedical Research, Archives of Iranian Medicine (2017)
31. Regional Disparities in Cancer Survival in Iran: Insight From a National Surveillance of Cancer Survival in Iran (Irancansurv), Cancer Epidemiology (2023)
32. Investigating Cancer Patients’ Quality of Life During the Covid-19 Outbreak: A Study From Iran, Shiraz E Medical Journal (2024)
33. Determine the Prevalence of Overweight and Obesity and Effective Factors in Iranian Females: A Population-Based Cross-Sectional Study, Acta Medica Iranica (2020)
34. Epidemiology and Trend of Cancers in the Province of Kerman: Southeast of Iran, Asian Pacific Journal of Cancer Prevention (2015)
35. Prevalence of Diabetes and Prediabetes, and Achievements in Diabetes Control in Iran; the Results of the Steps of 2016, Archives of Iranian Medicine (2022)
36. Dos and Don’Ts in Designing a Computerized Oral and Lip Squamous Cell Cancer Registry, BMC Health Services Research (2023)
37. Cigarette and Water-Pipe Use in Iran: Geographical Distribution and Time Trends Among the Adult Population; a Pooled Analysis of National Steps Surveys, 2006-2009, Archives of Iranian Medicine (2017)
38. The Trend in Histological Changes and the Incidence of Esophagus Cancer in Iran (2003–2008), International Journal of Preventive Medicine (2016)
39. Translation and Validation of the Persian Version of Godin Leisure-Time Exercise Questionnaire in Patients With Multiple Sclerosis, BMC Neurology (2021)
40. Intraoperative Assessment of High-Risk Thyroid Nodules Based on Electrical Impedance Measurements: A Feasibility Study, Diagnostics (2022)
41. Colorectal Cancer Screening Pilot Project in Tehran-Iran, a Feasibility Study, Archives of Iranian Medicine (2023)
42. Socioeconomic Gradient in Physical Activity: Findings From the Persian Cohort Study, BMC Public Health (2019)
43. The Epidemiological and Histological Trend of Bladder Cancer in Iran, Journal of Cancer Research and Therapeutics (2018)
44. Prevalence of Tobacco Use in Adults; 2016 Nationally Representative Household Survey in Iran, International Journal of Preventive Medicine (2022)
45. A Systematic Review of the Effects of Ketogenic Diet on Treatment Outcomes and Quality of Life in Breast Cancer Patients, Iranian Journal of Obstetrics# Gynecology and Infertility (2023)
46. Geographical Patterning of Physical Activity Prevalence in Iran: Spatial Analysis of 4 Pooled National Health Surveys Among 119,560 Adults, Journal of Physical Activity and Health (2019)
47. Trends in Incidence of Prostate Cancer in Iran and Its 31 Provinces During 2003 - 2016, International Journal of Cancer Management (2023)
48. Why Physical Inactivity Level Has Increased in the Iranian Population During the Past Decade? a Delphi Technique, Asian Journal of Sports Medicine (2020)
49. A National and Sub-National Metaregression of the Trend of Insufficient Physical Activity Among Iranian Adults Between 2001 and 2016, Scientific Reports (2021)
50. Zero and Five End-Digit Preference and Blood Pressure Quality of Care Revisited, Archives of Iranian Medicine (2017)