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Acifluorfen, Sodium Salt Publisher



Noruzi M1 ; Sharifzadeh M2
Authors
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Authors Affiliations
  1. 1. Faculty of Pharmacy, Pharmaceutical Sciences Research Center (PSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran
  2. 2. Faculty of Pharmacy, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran

Source: Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 Published:2023


Abstract

Acifluorfen is an herbicide. In nature, sodium Acifluorfen decomposes into Acifluorfen, which is toxic to plant cell membranes. It can be used before or after the annual broadleaf weeds and grasses have emerged to suppress them. Acifluorfen peroxidizes lipids in membranes due to its capacity to inhibit the enzyme protoporphyrinogen oxidase. Orally, topically, or inhaled administration of sodium Acifluorfen has been observed to have negligible acute toxicity. Damage to the liver is the most common type of chronic toxicity effect. This herbicide is probably carcinogenic in humans. © 2024 Elsevier Inc. All rights reserved.
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