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The Interphase Degradation in a Nanobiosensor Including Biopolymers and Carbon Nanotubes Publisher



Zare Y1 ; Rhim SS2 ; Rhee KY2
Authors
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Authors Affiliations
  1. 1. Biomaterials and Tissue Engineering Research Group, Department of Interdisciplinary Technologies, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran
  2. 2. Department of Mechanical Engineering (BK21 Four), College of Engineering, Kyung Hee University, Yongin, South Korea

Source: Sensors and Actuators# A: Physical Published:2021


Abstract

In this paper, a degradation nanobiosensor comprising two biopolymers as poly (lactic acid) (PLA) and poly (ethylene oxide) (PEO) as well as carbon nanotubes (CNT) is developed. The electrical conductivity of the samples for the period of degradation in phosphate-buffered saline (PBS) solution is analyzed focusing on interphase degradation. Furthermore, a model for the conductivity of examples is advanced by CNT properties, filler wettability by polymer medium, interphase depth, degradation portion and tunneling distance. The model's calculations are linked to the experimental facts and all parameters’ impacts on the conductivity of the decayed examples are described. The predictions of the suggested model sufficiently follow the empirical data. The interphase thickness dwindles during degradation and a high content of CNT largely eliminates the polymer and interphase region, because CNT accelerate the degradation. Both thick interphase and short tunnels obtain the high conductivity, while either thin interphase or a large tunnel causes an insulated example, since thin interphase or a big tunnel prevents the electron transferring. This study can provide a simple approach to calculate and optimize the conductivity to predict the behavior of a degradation nanobiosensor. © 2021
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