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Genomic Resources for Wild Populations of the House Mouse, Mus Musculus and Its Close Relative Mus Spretus Publisher Pubmed



Harr B1 ; Karakoc E1, 8 ; Neme R1, 9 ; Teschke M1, 10 ; Pfeifle C1 ; Pezer Z1, 11 ; Babiker H1 ; Linnenbrink M1 ; Montero I1, 12 ; Scavetta R1, 13 ; Abai MR2 ; Molins MP3 ; Schlegel M4, 14 ; Ulrich RG4 Show All Authors
Authors
  1. Harr B1
  2. Karakoc E1, 8
  3. Neme R1, 9
  4. Teschke M1, 10
  5. Pfeifle C1
  6. Pezer Z1, 11
  7. Babiker H1
  8. Linnenbrink M1
  9. Montero I1, 12
  10. Scavetta R1, 13
  11. Abai MR2
  12. Molins MP3
  13. Schlegel M4, 14
  14. Ulrich RG4
  15. Altmuller J5, 6
  16. Franitza M5, 7
  17. Buntge A1, 15
  18. Kunzel S1
  19. Tautz D1

Source: Scientific Data Published:2016


Abstract

Wild populations of the house mouse (Mus musculus) represent the raw genetic material for the classical inbred strains in biomedical research and are a major model system for evolutionary biology. We provide whole genome sequencing data of individuals representing natural populations of M. m. domesticus (24 individuals from 3 populations), M. m. helgolandicus (3 individuals), M. m. musculus (22 individuals from 3 populations) and M. spretus (8 individuals from one population). We use a single pipeline to map and call variants for these individuals and also include 10 additional individuals of M. m. castaneus for which genomic data are publically available. In addition, RNAseq data were obtained from 10 tissues of up to eight adult individuals from each of the three M. m. domesticus populations for which genomic data were collected. Data and analyses are presented via tracks viewable in the UCSC or IGV genome browsers. We also provide information on available outbred stocks and instructions on how to keep them in the laboratory. © The Author(s) 2016.
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