Ligand-Free, Copper-Catalyzed, One-Pot, Three-Component Synthesis of Novel 1,2,3-Triazole-Linked Indoles in Magnetized Water

Ligand-Free, Copper-Catalyzed, One-Pot, Three-Component Synthesis of Novel 1,2,3-Triazole-Linked Indoles in Magnetized Water Publisher

Bakherad M¹ ; Keivanloo A¹ ; Bakherad Z² ; Toozandejani Z¹ ; Mahdavi M³

Show Affiliations

1. Faculty of Chemistry, Shahrood University of Technology, Shahrood, Iran
2. Food and Drug Laboratories Research Center, Food and Drug Organization, MOH & ME, Tehran, Iran
3. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Science Institute, Tehran, Iran

Source: Journal of the Chinese Chemical Society Published:2019

Abstract

Magnetized water (MW) is used as a green and new solvent-promoting medium for the one-pot, three-component synthesis of novel 1,2,3-triazole-linked indoles catalyzed by copper iodide. A broad range of 2-aryl-1-(prop-2-ynyl)-1H-indole-3-carbaldehydes were reacted with alkyl halides and sodium azide via copper-catalyzed azide–alkyne cycloaddition reactions in MW in the absence of any ligand. This method offers the advantages of short reaction times, green procedure, low cost, simple work-up, quantitative reaction yields, and no need for any organic solvent. © 2019 The Chemical Society Located in Taipei & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Style	Citing Format
MLA	Bakherad M, et al.. "Ligand-Free, Copper-Catalyzed, One-Pot, Three-Component Synthesis of Novel 1,2,3-Triazole-Linked Indoles in Magnetized Water." Journal of the Chinese Chemical Society, vol. 66, no. 6, 2019, pp. 674-682.
APA	Bakherad M, Keivanloo A, Bakherad Z, Toozandejani Z, Mahdavi M (2019). Ligand-Free, Copper-Catalyzed, One-Pot, Three-Component Synthesis of Novel 1,2,3-Triazole-Linked Indoles in Magnetized Water. Journal of the Chinese Chemical Society, 66(6), 674-682.
Chicago	Bakherad M, Keivanloo A, Bakherad Z, Toozandejani Z, Mahdavi M. "Ligand-Free, Copper-Catalyzed, One-Pot, Three-Component Synthesis of Novel 1,2,3-Triazole-Linked Indoles in Magnetized Water." Journal of the Chinese Chemical Society 66, no. 6 (2019): 674-682.
Harvard	Bakherad M et al. (2019) 'Ligand-Free, Copper-Catalyzed, One-Pot, Three-Component Synthesis of Novel 1,2,3-Triazole-Linked Indoles in Magnetized Water', Journal of the Chinese Chemical Society, 66(6), pp. 674-682.
Vancouver	Bakherad M, Keivanloo A, Bakherad Z, Toozandejani Z, Mahdavi M. Ligand-Free, Copper-Catalyzed, One-Pot, Three-Component Synthesis of Novel 1,2,3-Triazole-Linked Indoles in Magnetized Water. Journal of the Chinese Chemical Society. 2019;66(6):674-682.
BibTex	@article{ author = {Bakherad M and Keivanloo A and Bakherad Z and Toozandejani Z and Mahdavi M}, title = {Ligand-Free, Copper-Catalyzed, One-Pot, Three-Component Synthesis of Novel 1,2,3-Triazole-Linked Indoles in Magnetized Water}, journal = {Journal of the Chinese Chemical Society}, volume = {66}, number = {6}, pages = {674-682}, year = {2019} }
RIS	TY - JOUR AU - Bakherad M AU - Keivanloo A AU - Bakherad Z AU - Toozandejani Z AU - Mahdavi M TI - Ligand-Free, Copper-Catalyzed, One-Pot, Three-Component Synthesis of Novel 1,2,3-Triazole-Linked Indoles in Magnetized Water JO - Journal of the Chinese Chemical Society VL - 66 IS - 6 SP - 674 EP - 682 PY - 2019 ER -

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