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Advances in Hematopoietic Stem Cell Transplantation in the Asia-Pacific Region: The Second Report From Apbmt 2005–2015 Publisher Pubmed



Iida M1 ; Kodera Y1 ; Dodds A2 ; Ho AYL3 ; Nivisonsmith I4 ; Akter MR5 ; Wu T6 ; Lie AKW7 ; Ghavamzadeh A8 ; Kang HJ9 ; Ong TC10 ; Gyi AA11 ; Farzana T12 ; Baylon H13 Show All Authors
Authors
  1. Iida M1
  2. Kodera Y1
  3. Dodds A2
  4. Ho AYL3
  5. Nivisonsmith I4
  6. Akter MR5
  7. Wu T6
  8. Lie AKW7
  9. Ghavamzadeh A8
  10. Kang HJ9
  11. Ong TC10
  12. Gyi AA11
  13. Farzana T12
  14. Baylon H13
  15. Gooneratne L14
  16. Tang JL15
  17. Bunworasate U16
  18. Huynh VM17
  19. Srivastava A18
  20. Okamoto S19
  21. Atsuta Y20
Show Affiliations
Authors Affiliations
  1. 1. Department of Promotion for Blood and Marrow Transplantation, Aichi Medical University School of Medicine, Nagakute, Japan
  2. 2. St. Vincent’s Pathology, St. Vincent’s Health Network Sydney, Australasian Bone Marrow Transplant Recipient Registry (ABMTRR), Sydney, Australia
  3. 3. Department of Haematology, Singapore General Hospital, Singapore, Singapore
  4. 4. Australasian Bone Marrow Transplant Recipient Registry (ABMTRR), Sydney, Australia
  5. 5. Department of Hematology & BMT, Dhaka Medical College & Hospital, Dhaka, Bangladesh
  6. 6. Department of Bone Marrow Transplantation, Ludaopei, Hematology & Oncology Center, Yanda International Hospital, Hebei, China
  7. 7. Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
  8. 8. Hematology, Oncology and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. Department of Pediatrics, Seoul National University College of Medicine, Seoul National University Cancer Research Institute, Seoul, South Korea
  10. 10. Department of Haematology, Ampang Hospital, Selangor Darul Ehsan, Malaysia
  11. 11. Department of Clinical Haematology, North Okkalapa General Hospital, Yangon, Myanmar
  12. 12. Department of Clinical Haematology, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan
  13. 13. Blood and Marrow Transplant Center, St. Luke’s Medical Center, Quezon City, Philippines
  14. 14. Faculty of Medicine, Sri Lanka and Central Hospital, University of Colombo, Colombo, Sri Lanka
  15. 15. Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
  16. 16. Research Collaborations in Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Division of Hematology, Chulalongkorn University, Bangkok, Thailand
  17. 17. Stem cell transplantation department, Blood Transfusion and Hematology Hospital, Ho Chi Minh, Viet Nam
  18. 18. Department of Haematology, Christian Medical College Hospital, Vellore, India
  19. 19. Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
  20. 20. Japanese Data Center for Hematopoietic Cell Transplantation (JDCHCT), Nagoya, Japan

Source: Bone Marrow Transplantation Published:2019


Abstract

Between 2005 and 2015, 138,165 hematopoietic stem cell transplantation (HSCT) were reported in 18 countries/regions in the Asia-Pacific region. In this report, we describe current trends in HSCT throughout the Asia-Pacific region and differences among nations in this region and various global registries. Since 2008, more than 10,000 HSCTs have been recorded each year by the Asia-Pacific Blood and Marrow Transplantation Group Data Center. Between 2005 and 2015, the greatest increase in the number of HSCTs was observed in Vietnam. Allogeneic HSCT was performed more frequently than autologous HSCT, and a majority of cases involved related donors. Regarding allogeneic HSCT, the use of cord blood has remained steady, especially in Japan, and the number of cases involving related HLA non-identical donors has increased rapidly, particularly in China. The incidence of hemoglobinopathy, a main indication for allogeneic HSCT in India, China, Iran, and Pakistan, increased nearly six-fold over the last decade. Among the 18 participating countries/regions, the transplant rate per population varied widely according to the absolute number of HSCTs and the national/regional population size. We believe that this report will not only benefit the AP region but will also provide information about HSCT to other regions worldwide. © 2019, Springer Nature Limited.