Regulation of Autophagy by Polyphenols: Paving the Road for Treatment of Neurodegeneration

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Regulation of Autophagy by Polyphenols: Paving the Road for Treatment of Neurodegeneration Publisher Pubmed

Nabavi SF¹ ; Sureda A² ; Dehpour AR^{3, 4} ; Shirooie S⁵ ; Silva AS^{6, 7} ; Devi KP⁸ ; Ahmed T⁹ ; Ishaq N⁹ ; Hashim R⁹ ; Sobarzosanchez E^{10, 11} ; Daglia M¹² ; Braidy N^{13, 16} ; Volpicella M¹⁴ ; Vacca RA¹⁵ Show All Authors

Nabavi SF¹
Sureda A²
Dehpour AR^{3, 4}
Shirooie S⁵
Silva AS^{6, 7}
Devi KP⁸
Ahmed T⁹
Ishaq N⁹
Hashim R⁹
Sobarzosanchez E^{10, 11}
Daglia M¹²
Braidy N^{13, 16}
Volpicella M¹⁴
Vacca RA¹⁵
Nabavi SM^{1, 17}

Show Affiliations

1. Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, 14359-16471, Iran
2. Research Group on Community Nutrition and Oxidative Stress (NUCOX) and CIBEROBN (Physiopathology of Obesity and Nutrition CB12/03/30038), University of Balearic Islands, Palma de Mallorca, E-07122, Balearic Islands, Spain
3. Department of Pharmacology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Experimental Medicine Research Centre, Tehran University of Medical Sciences, Tehran, Iran
5. School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, 6734667149, Iran
6. National Institute for Agricultural and Veterinary Research (INIAV), I.P., Vairao, 4480, Vila do Conde, Portugal
7. Center for Study in Animal Science (CECA), ICETA, University of Oporto, Oporto, 4051-401, Portugal
8. Department of Biotechnology, Alagappa University, Karaikudi, 630 003, Tamil Nadu, India
9. Atta-ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Pakistan
10. Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain
11. Instituto de Investigacion e Innovacion en Salud, Facultad de Ciencias de la Salud, Universidad Central de Chile, Santiago, Chile
12. Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Pavia, 27100, Italy
13. Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Australia
14. Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy
15. Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies National Council of Research, Bari, Italy
16. Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, Australia
17. Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, P.O. Box 19395-5487, Tehran, Iran

Source: Biotechnology Advances Published:2018

Abstract

In the present paper, we will discuss on the importance of autophagy in the central nervous system, and outline the relation between autophagic pathways and the pathogenesis of neurodegenerative disorders. The potential therapeutic benefits of naturally occurring phytochemicals as pharmacological modulators of autophagy will also be addressed. Our findings provide renewed insight on the molecular modes of protection by polyphenols, which is likely to be at least in part mediated not only by their potent antioxidant and anti-inflammatory effects, but also through modulation of autophagic processes to remove the aberrant protein aggregates. © 2017 Elsevier Inc.

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Style	Citing Format
MLA	Nabavi SF, et al.. "Regulation of Autophagy by Polyphenols: Paving the Road for Treatment of Neurodegeneration." Biotechnology Advances, vol. 36, no. 6, 2018, pp. 1768-1778.
APA	Nabavi SF, Sureda A, Dehpour AR, Shirooie S, Silva AS, Devi KP, Ahmed T, Ishaq N, Hashim R, Sobarzosanchez E, Daglia M, Braidy N, Volpicella M, Vacca RA, Nabavi SM (2018). Regulation of Autophagy by Polyphenols: Paving the Road for Treatment of Neurodegeneration. Biotechnology Advances, 36(6), 1768-1778.
Chicago	Nabavi SF, Sureda A, Dehpour AR, Shirooie S, Silva AS, Devi KP, Ahmed T, et al.. "Regulation of Autophagy by Polyphenols: Paving the Road for Treatment of Neurodegeneration." Biotechnology Advances 36, no. 6 (2018): 1768-1778.
Harvard	Nabavi SF et al. (2018) 'Regulation of Autophagy by Polyphenols: Paving the Road for Treatment of Neurodegeneration', Biotechnology Advances, 36(6), pp. 1768-1778.
Vancouver	Nabavi SF, Sureda A, Dehpour AR, Shirooie S, Silva AS, Devi KP, et al.. Regulation of Autophagy by Polyphenols: Paving the Road for Treatment of Neurodegeneration. Biotechnology Advances. 2018;36(6):1768-1778.
BibTex	@article{ author = {Nabavi SF and Sureda A and Dehpour AR and Shirooie S and Silva AS and Devi KP and Ahmed T and Ishaq N and Hashim R and Sobarzosanchez E and Daglia M and Braidy N and Volpicella M and Vacca RA and Nabavi SM}, title = {Regulation of Autophagy by Polyphenols: Paving the Road for Treatment of Neurodegeneration}, journal = {Biotechnology Advances}, volume = {36}, number = {6}, pages = {1768-1778}, year = {2018} }
RIS	TY - JOUR AU - Nabavi SF AU - Sureda A AU - Dehpour AR AU - Shirooie S AU - Silva AS AU - Devi KP AU - Ahmed T AU - Ishaq N AU - Hashim R AU - Sobarzosanchez E AU - Daglia M AU - Braidy N AU - Volpicella M AU - Vacca RA AU - Nabavi SM TI - Regulation of Autophagy by Polyphenols: Paving the Road for Treatment of Neurodegeneration JO - Biotechnology Advances VL - 36 IS - 6 SP - 1768 EP - 1778 PY - 2018 ER -

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