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The Association Between B Vitamins and the Risk of Covid-19 Publisher Pubmed



Darand M1 ; Hassanizadeh S1 ; Martami F2 ; Shams S3, 4 ; Mirzaei M5 ; Hosseinzadeh M3, 4
Authors
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Authors Affiliations
  1. 1. Department of Clinical Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Isfahan, Iran
  3. 3. Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  4. 4. Department of Nutrition, School of Public Health, Shahid Sadughi University of Medical Sciences, Yazd, Iran
  5. 5. Yazd Cardiovascular Research Centre, Non-communicable Disease Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Source: British Journal of Nutrition Published:2023


Abstract

The fast spread of the coronavirus disease 2019 (COVID-19) epidemic and its high mortality were quickly noticed by the health community. B vitamins are essential micronutrients for the body with antioxidant, anti-inflammatory and immune-regulating properties. The present study can provide a comprehensive picture of the associations between B vitamins and COVID-19 incidence. This study was undertaken on 9189 adult participants of the Yazd Health Study (YaHS) and Taghzieh Mardom-e-Yazd (TAMIZ) study aged 20 to 69 years. Data on dietary intakes were obtained using a validated FFQ. Multivariable logistic regression analysis was used to evaluate the association between B vitamins and COVID-19. Our findings indicated that participants in the fourth quartile of vitamin B5 intake compared with the first quartile had a protective effect against COVID-19 (OR: 0·53, 95 % CI 0·28, 0·99, P-trend = 0·02) after adjustment for all possible confounds in model 3. In addition, participants in the third quartile of vitamin B12 intake compared with the first quartile (OR: 0·63, 95 % CI 0·40, 0·98, P-trend = 0·11) had fewer odds of COVID-19 after full adjustments for confounders. Our findings indicated no significant relationship between dietary intake of vitamin B1, B2, B3, B9 and B-complex and COVID-19. A higher intake of vitamin B5 could reduce the odds of COVID-19 by 47 %, and a moderate intake of vitamin B12 had a protective effect on COVID-19. Although our study has promising results, stronger clinical studies are needed. © The Author(s), 2022. Published by Cambridge University Press on behalf of The Nutrition Society.
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