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Nutraceuticals for Multiple Sclerosis



Pour PM1 ; Shah MA2 ; Chauhdary Z2 ; Rasul A3 ; Saadullah M4 ; Khan A5 ; Alharrasi A5 ; Liaqat M6 ; Zafar M7 ; Khan AH8 ; Blundell R9
Authors
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Authors Affiliations
  1. 1. Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan
  3. 3. Department of Zoology, Faculty of Life Sciences, Government College University, Faisalabad, Pakistan
  4. 4. Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan
  5. 5. Natural and Medical Sciences Research Centre, University of Nizwa, Nizwa, Oman
  6. 6. Department of Physics, Faculty of Science, Okara University, Okara, Pakistan
  7. 7. Department of Plant Sciences, Quaid-i-Azam University, Islamabad, Pakistan
  8. 8. Department of Pharmacy, Forman Christian College (A Chartered University), Lahore, Pakistan
  9. 9. American University of Malta, Triq Dom Mintoff, Bormla, Malta

Source: Bioactive Nutraceuticals for Brain Disorders Published:2021

Abstract

Multiple sclerosis is an inflammatory disease of the central nervous system associated with T-cell mediated immune response against myelin sheath, as well as oxidative stress. Numbness, electric shock sensation and visual problems are some of its clinical symptoms. Currently there is no cure for the disease and the treatments available serve only to slow the progression of the disease and for symptom control. This chapter highlights the therapeutic relevance of nutraceuticals against both neurodegeneration and neuronal inflammation. Nutraceuticals such as phenolic acids, non-flavonoid polyphenols, flavonoid polyphenols, diterpenes, and organic sulfur compounds have all been shown to possess an anti-inflammatory and neuroprotective effect against multiple sclerosis. This chapter aims to deliver both the advantages and disadvantages of consuming these nutraceuticals for the hope of alleviating the progression of multiple sclerosis. © 2021 Nova Science Publishers, Inc. All rights reserved.
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