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Neuroprotective Effects of Glycosides Publisher



Ebrahimi MS1, 2 ; Hosseini Z3 ; Khatami A4 ; Abbasikolli M5 ; Sadri Nahand J4 ; Kouchaki E6 ; Mirzaei H7
Authors

Source: Phytonutrients and Neurological Disorders: Therapeutic and Toxicological Aspects Published:2023


Abstract

Advantaged from the remarkable penetrative ability into blood–brain barrier, glycosides regulate several signaling pathways in brain cells resulting in suppressed neurotoxins-associated apoptosis, enhanced differentiation and survival and other neuroprotective effects. Beside antiinflammatory and functional benefits of glycoside compounds, the dietary form of glycosides have successfully led to inhibitory effects on senile neurodegeneration and cognitive impairment, if consumed on a regular basis throughout the life. Therefore, glycosides may further meet pharmaceutical features needed for developing a noble brain-protective drug designed for improving brain activity and hindering neurodegenerative diseases. © 2023 Elsevier Inc. All rights reserved.
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