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The Role of Cobalamin in Multiple Sclerosis: An Update Publisher

Summary: Review suggests vitamin B12 may protect neurons in MS, but no direct deficiency link. #MultipleSclerosis #VitaminB12

Golabi M1 ; Kazemi D2 ; Chadeganipour AS3 ; Fouladseresht H1 ; Sullman MJM5, 6 ; Ghezelbash B4 ; Dastgerdi AY7 ; Eskandari N1
Authors

Source: Inflammation Published:2024


Abstract

Multiple sclerosis (MS) is a neurodegenerative condition that results in axonal and permanent damage to the central nervous system, necessitating healing owing to autoimmune reactions and persistent neuroinflammation. Antioxidant and anti-inflammatory drugs are essential for the management of oxidative stress and neuroinflammation. Additionally, multivitamin supplementation, particularly vitamin B12 (cobalamin), may be beneficial for neuronal protection. Although there is no documented connection between vitamin B12 deficiency and MS, researchers have explored its potential as a metabolic cause. This review highlights the therapeutic benefits of cobalamin (Cbl) in patients with MS. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.
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