Case Report: Tumefactive Brain Lesions in Patients With Neuromyelitis Optica Spectrum Disorder Publisher



Manouchehri N^{1, 2} ; Nehzat N¹ ; Mirmosayeb O^{1, 3} ; Shaygannejad V^{1, 2} ; Barzegar M^{1, 3}
Source: Caspian Journal of Neurological Sciences Published:2019

Abstract

Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune neurological disorder that is characterized by optic neuritis and longitudinally-extended transverse myelitis lesions in spinal segments. Magnetic Resonance Imaging (MRI) findings are part of the diagnostic process in NMOSD patients, and abnormal lesion patterns may cause deviation from a correct diagnosis. Clinical Presentation and Intervention: A 43-year-old female patient with abrupt cognitive loss, motor dysfunction and tumefactive spread of the demyelinating lesions in her brain presented to the Neurology Clinic of Kashani Hospital. Anti Aquaporine 4(AQP-4) antibody was observed, and the patient responded well to the NMOSD treatment. Conclusion: NMOSD can be considered a differential diagnosis during an episode of Fulminant Demyelinating Disorder (FDD) with the tumefactive spread of the lesions. © 2018 The Authors. This is an open access article under the CC-By-NC license.