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Mri Signs of Cns Demyelinating Diseases Publisher Pubmed



Etemadifar M1 ; Ashourizadeh H2 ; Nouri H3, 4 ; Kargaran PK5 ; Salari M6 ; Rayani M3 ; Aghababaee A3 ; Abhari AP3, 4
Authors
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Authors Affiliations
  1. 1. Department of Neurosurgery, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Functional Neurosurgery Research Center, Shohada Tajrish Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Alzahra Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Network of Immunity in Infection, Malignancy, and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Isfahan, Iran
  5. 5. Departments of Cardiovascular Medicine, Center for Regenerative Medicine, Mayo Clinic, Rochester, MN, United States
  6. 6. Department of Neurological Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Multiple Sclerosis and Related Disorders Published:2021


Abstract

The differential diagnosis of the central nervous system (CNS) demyelinating diseases can be greatly facilitated by visualization and appreciation of pathognomonic radiological signs, visualized on magnetic resonance imaging (MRI) sequences. Given the distinct therapeutic approaches for each of these diseases, a decisive and reliable diagnosis in patients presenting with demyelination-associated symptoms is of crucial value. Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are major examples of such conditions, each possessing a number of MRI signs, closely associated with the disorder. This pictorial review aims to describe seventeen pathognomonic MRI signs associated with several CNS demyelinating disorders including MS, NMOSD, myelin oligodendrocyte glycoprotein-associated disease, Balo’s concentric sclerosis, metachromatic leukodystrophy, progressive multifocal leukoencephalopathy, and neurosarcoidosis. © 2020
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