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Fear of Relapse, Social Support, and Psychological Well-Being (Depression, Anxiety, and Stress Level) of Patients With Multiple Sclerosis (Ms) During the Covid-19 Pandemic Stage Publisher Pubmed



Shaygannejad V1, 2 ; Mirmosayyeb O1, 2, 3 ; Nehzat N2 ; Ghajarzadeh M3, 4
Authors
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Authors Affiliations
  1. 1. Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Universal Council of Epidemiology (UCE), Universal Scientific Education and Research Network (USERN), Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Multiple Sclerosis Research Center Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Neurological Sciences Published:2021


Abstract

Background: Psychological well-being assessment during the COVID-19 pandemic is essential for patients with multiple sclerosis (MS). The goal of this study is to evaluate fear of relapse, social support, and psychological well-being (depression, anxiety, and stress level) of Iranian patients with MS during the COVID-19 pandemic stage. Methods: One hundred and sixty-five patients were enrolled. We asked all cases to fill valid and reliable Persian version of depression, anxiety, and stress scale (DASS-21), perceived social support, and fear of relapse scale questionnaires. Results: One hundred and sixty-five patients were enrolled. Female to male ratio was (F/M) = 4.6. Mean age and mean duration of disease were 35.3±8.6 and 7.1±5 years, respectively. Mean scores of social support, DASS, and FoR questionnaires were 63.1±16.8, 16.4±13.4, and 51.4±17.3, respectively. There was a significant negative correlation between social support and FoR scores and also significant positive correlations between components of DASS and FoR. Linear regression analysis by considering FoR as dependent variable and age, sex, marital status, duration of the disease, and EDSS as dependent variables showed that sex was an independent predictor of FoR score. Conclusion: Psychological well-being as well as fear of relapse should be considered in patients with MS during the COVID-19 pandemic stage. © 2021, Fondazione Societa Italiana di Neurologia.
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