The Study of the Serum Manganese Concentration in the Bladder Cancer Patients in Comparison With Healthy Subjects

The Study of the Serum Manganese Concentration in the Bladder Cancer Patients in Comparison With Healthy Subjects

Mazdak H¹ ; Mirkheshti N² ; Movahedian A³ ; Yazdekhasti F⁴ ; Behzad E⁴ ; Shafieian M⁴ ; Shamszadeh Z⁴

Show Affiliations

1. Department of Urology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2. Hakiman Shargh Research Company, Isfahan, Iran
3. Department of Biochemistry, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran
4. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2008

Abstract

Background: Manganese (Mn) is one the more important trace elements in the humans. Mn plays an important role in antioxidant defences and it is an essential cofactor for a number of enzymes. Some studies have revealed that Mn deficiency is teratogenic. The relationship of Mn deficiency and cancer induction also has been studied in some studies. We evaluated the serum Mn concentration in patients with bladder cancer in comparison with healthy individuals. Methods: During this cross sectional study, 51 patients with bladder cancer and 58 normal subjects were selected regarding the inclusion and exclusion criteria. Blood samples were collected after 8 hours of fasting. The Mn serum concentration was measured in all samples and copamared between two groups. Findings: Mean of serum Mn concentration was 1.3 ± 0.39 μg/l in bladder cancer patients and 1.87 ± 0.84μg/l in control group. There was a significant difference between two groups (p < 0.001). Conclusion: According to the results of this study Mn serum concentration had significant decrease in bladder cancer patients in comparison with normal subjects. This result is similar to the other researches done in different cancers. Regarding the high Mn level in fresh foods and vegetables, consumption of these nutrients, is recommended in high risk individuals for bladder cancer. © 2008, Isfahan University of Medical Sciences(IUMS). All rights reserved.

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Style	Citing Format
MLA	Mazdak H, et al.. "The Study of the Serum Manganese Concentration in the Bladder Cancer Patients in Comparison With Healthy Subjects." Journal of Isfahan Medical School, vol. 26, no. 90, 2008, pp. -.
APA	Mazdak H, Mirkheshti N, Movahedian A, Yazdekhasti F, Behzad E, Shafieian M, Shamszadeh Z (2008). The Study of the Serum Manganese Concentration in the Bladder Cancer Patients in Comparison With Healthy Subjects. Journal of Isfahan Medical School, 26(90), -.
Chicago	Mazdak H, Mirkheshti N, Movahedian A, Yazdekhasti F, Behzad E, Shafieian M, Shamszadeh Z. "The Study of the Serum Manganese Concentration in the Bladder Cancer Patients in Comparison With Healthy Subjects." Journal of Isfahan Medical School 26, no. 90 (2008): -.
Harvard	Mazdak H et al. (2008) 'The Study of the Serum Manganese Concentration in the Bladder Cancer Patients in Comparison With Healthy Subjects', Journal of Isfahan Medical School, 26(90), pp. -.
Vancouver	Mazdak H, Mirkheshti N, Movahedian A, Yazdekhasti F, Behzad E, Shafieian M, et al.. The Study of the Serum Manganese Concentration in the Bladder Cancer Patients in Comparison With Healthy Subjects. Journal of Isfahan Medical School. 2008;26(90):-.
BibTex	@article{ author = {Mazdak H and Mirkheshti N and Movahedian A and Yazdekhasti F and Behzad E and Shafieian M and Shamszadeh Z}, title = {The Study of the Serum Manganese Concentration in the Bladder Cancer Patients in Comparison With Healthy Subjects}, journal = {Journal of Isfahan Medical School}, volume = {26}, number = {90}, pages = {-}, year = {2008} }
RIS	TY - JOUR AU - Mazdak H AU - Mirkheshti N AU - Movahedian A AU - Yazdekhasti F AU - Behzad E AU - Shafieian M AU - Shamszadeh Z TI - The Study of the Serum Manganese Concentration in the Bladder Cancer Patients in Comparison With Healthy Subjects JO - Journal of Isfahan Medical School VL - 26 IS - 90 SP - EP - PY - 2008 ER -

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